Characterisation of cytochroems P450 in experimental minipigs
Public support
Provider
Ministry of Education, Youth and Sports
Programme
COST
Call for proposals
COST 4 (SMSM200600OC1)
Main participants
—
Contest type
VS - Public tender
Contract ID
1041/2006-32
Alternative language
Project name in Czech
Charakterizace cytochromů P450 u experimentálních miniprasat
Annotation in Czech
charakterizace cytochromu P450 miniprasat a porovnání důležitých charakteristik s P450 systemem člověka
Scientific branches
R&D category
AP - Applied research
CEP classification - main branch
GI - Farm animal breeding and farm animal pedigree breeding
CEP - secondary branch
—
CEP - another secondary branch
—
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
40203 - Husbandry
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
In the course of this project, bacterial systems expressing minipig cytochromes P450 2E1 and 3A29 were prepared enabling comparison of their properties with human enzymes. Minipig liver P450s were also characterized in vitro and new system for drug testing was validated and published.
Solution timeline
Realization period - beginning
Mar 1, 2006
Realization period - end
Jun 30, 2009
Project status
U - Finished project
Latest support payment
Feb 16, 2009
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP10-MSM-OC-U/02:2
Data delivery date
Jun 30, 2011
Finance
Total approved costs
3,415 thou. CZK
Public financial support
1,600 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
1,902 thou. CZK