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OC 136

Combined chemical and enzymatic synthesis of complex multivalent glycoconjungates - ways to new materials and glycodrugs

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    COST

  • Call for proposals

    COST 4 (SMSM200600OC1)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    1140/2010-32

Alternative language

  • Project name in Czech

    Kombinovaná chemická a enzymová syntéza komplexních multivalentních glykokonjugátů ? cesty k novým materiálům a glykoterapeutikům.

  • Annotation in Czech

    příprava glykomimetik na bázi polyaminoamido dendrimerů (PAMAM) a kalixarenů a vypracovat metodiku enzymových modifikací

Scientific branches

  • R&D category

    AP - Applied research

  • CEP classification - main branch

    CE - Biochemistry

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    "New glycosylazide donor for glycosidases was developed. Extensive multivalent ligand optimizations for antitumor NK cell activation void of apoptotic effects - these ligands have potential to pass to the preclinical testing."

Solution timeline

  • Realization period - beginning

    Mar 1, 2006

  • Realization period - end

    Jun 30, 2010

  • Project status

    U - Finished project

  • Latest support payment

    Mar 1, 2010

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP11-MSM-OC-U/01:1

  • Data delivery date

    Jun 30, 2011

Finance

  • Total approved costs

    2,244 thou. CZK

  • Public financial support

    1,633 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    611 thou. CZK