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OC 153

Fatty acid- and glucose-induced changes in gene expression of peroxisome proliferator-activated receptor (PPAR) signalling cascade molecules

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    COST

  • Call for proposals

    COST 5 (SMSM2007OC2)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    1143/2010-32

Alternative language

  • Project name in Czech

    Změny genetické exprese signálních molekul funkčně spřažených s receptory aktivovanými proliferátory peroxisomů (PPAR). Indukce změn mastnými kyselinami a glukózou.

  • Annotation in Czech

    studium účinků hlavních energetických substrátu na expresi genu hlavních molekulárních složek signálních molekul

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    FB - Endocrinology, diabetology, metabolism, nutrition

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30202 - Endocrinology and metabolism (including diabetes, hormones)

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    In this project, changes in relative mRNA levels of several transcriptional factors ? peroxisome proliferator-activated receptors (PPARs)-?, -?1, and -?2 ? and their coactivators PGC-1? a -1? in HepG2 cells were studied using quantitative RT-PCR.

Solution timeline

  • Realization period - beginning

    Jan 1, 2007

  • Realization period - end

    Dec 31, 2010

  • Project status

    U - Finished project

  • Latest support payment

    Mar 1, 2010

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP11-MSM-OC-U/01:1

  • Data delivery date

    Jun 30, 2011

Finance

  • Total approved costs

    2,910 thou. CZK

  • Public financial support

    1,895 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    1,015 thou. CZK