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Non Covalent DNA Recognition Strategies for Design and Synthesis of New Metallodrugs

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    COST

  • Call for proposals

    COST 3 (SMSM200300004)

  • Main participants

    Biofyzikální ústav AV ČR, v. v. i.

  • Contest type

    VS - Public tender

  • Contract ID

Alternative language

  • Project name in Czech

    Strategie pro návrh a syntézu nových léčiv odvozených od kovových sloučenin pro nekovalentní rozlišení DNA

  • Annotation in Czech

    Strategie pro návrh a syntézu nových léčiv odvozených od kovových sloučenin pro nekovalentní rozlišení DNA

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FR - Pharmacology and apothecary chemistry

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30104 - Pharmacology and pharmacy

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    It was found that metallo-supramolecular cylinders bound to DNA three-way junctions, unwound DNA and affected in a specific way its interactions with nucleases. The results were summarized in 1 script prepared for publication in an international journal

Solution timeline

  • Realization period - beginning

    Jan 1, 2003

  • Realization period - end

    Jan 1, 2005

  • Project status

    U - Finished project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP06-MSM-OC-U/04:2

  • Data delivery date

    May 28, 2008

Finance

  • Total approved costs

    2,190 thou. CZK

  • Public financial support

    1,000 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    1,190 thou. CZK