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OC08007

Role of energy status of adipocytes in adipokine secretion

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    COST

  • Call for proposals

    COST 6 (SMSM2008OC3)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    1146/2010-32

Alternative language

  • Project name in Czech

    Role energetického stavu adipocytů v sekreci adipokinů

  • Annotation in Czech

    Cílem projektu je testovat hypotézu, že modulace energetického stavu tukových buněk vede ke změně sekreční aktivity tukové tkáně a tím i ke změnám v inzulínové citlivosti, glukózového a lipidového metabolismu celého organismu.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    FB - Endocrinology, diabetology, metabolism, nutrition

  • CEP - secondary branch

    ED - Physiology

  • CEP - another secondary branch

    CE - Biochemistry

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30105 - Physiology (including cytology)<br>30202 - Endocrinology and metabolism (including diabetes, hormones)

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Within the project we have demonstrated (i) the important role of AMPK, a cellular sensor of energy status, in beneficial effects of n-3 fatty acids (n-3 PUFA), (ii) the additive effects of the combination treatment of n-3 PUFA and antidiabetic agents ?thiazolinediones on insulin sensitivity.

Solution timeline

  • Realization period - beginning

    Jan 1, 2008

  • Realization period - end

    Jun 30, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Feb 22, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-MSM-OC-U/01:1

  • Data delivery date

    Jul 12, 2012

Finance

  • Total approved costs

    2,439 thou. CZK

  • Public financial support

    2,439 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK