Cascade chemoenzymatic reactions of nitriles

Provider

Ministry of Education, Youth and Sports

Programme

COST

Call for proposals

COST 7 (SMSM2009OC4)

Main participants

—

Contest type

VS - Public tender

Contract ID

1080/2011-320

Project name in Czech

Kaskádové chemoenzymatické reakce nitrilů

Annotation in Czech

Kombinací (bio)katalytických kroků provést v laboratorních podmínkách transformace nitrilů vedoucí ke sloučeninám průmyslového významu nebo využitelné pro screening enzymů.

R&D category

ZV - Basic research

CEP classification - main branch

CC - Organic chemistry

CEP - secondary branch

CE - Biochemistry

CEP - another secondary branch

EE - Microbiology, virology

OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

10401 - Organic chemistry<br>10606 - Microbiology<br>10607 - Virology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods

Provider evaluation

V - Vynikající výsledky projektu (s mezinárodním významem atd.)

Project results evaluation

Cascade reactions catalyzed chemically and by enzymes (nitrile hydratases, amidases, nitrilases, lipases) were applied to prepare pharmaceutical products on laboratory scale (cyclophellitols - glucosidase inhibitors, hydroxamates - chelating agents), intermediates of natural compounds or semisynthetic antibiotics etc. The principle of cascade reactions was also used for enzyme assays.

Realization period - beginning

Apr 1, 2009

Realization period - end

Jun 30, 2012

Project status

U - Finished project

Latest support payment

Feb 27, 2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data delivery code

CEP13-MSM-OC-U/01:1

Data delivery date

Jun 28, 2013

Total approved costs

1,700 thou. CZK

Public financial support

1,700 thou. CZK

Other public sources

0 thou. CZK

Non public and foreign sources

0 thou. CZK