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OC10053

DENDRIMERS IN BIOMEDICAL APPLICATIONS

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    COST

  • Call for proposals

    COST 8 (SMSM2010OC5)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    1081/2011-320

Alternative language

  • Project name in Czech

    Dendrimery v biomedicínských aplikacích

  • Annotation in Czech

    Ve spolupráci se zahraničními pracovišti podpořit základní výzkum v oblasti použití dendrimerů pro pro léčbu rakoviny, Alzheimerovy nemoci a.j. a v oblasti využití dendrimerů pro nanobioanalytická zařízení.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    CE - Biochemistry

  • CEP - secondary branch

    CD - Macromolecular chemistry

  • CEP - another secondary branch

    CF - Physical chemistry and theoretical chemistry

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10403 - Physical chemistry<br>10404 - Polymer science<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    We have obtained and original knowledge about the interaction of four degradable carbosilane dendrimes with single stranded oligonucleotides GEM 91 and ANTI TAR valuable for development of novel drug-delivery vehicules for gene therapy (anti-sense therapy). We have documented self-assembled processes of maltose-modified PPI dendrimers with oligonucleotides (dendriplexes).

Solution timeline

  • Realization period - beginning

    May 1, 2010

  • Realization period - end

    Dec 31, 2012

  • Project status

    U - Finished project

  • Latest support payment

    Feb 27, 2012

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP13-MSM-OC-U/01:1

  • Data delivery date

    Jun 28, 2013

Finance

  • Total approved costs

    2,401 thou. CZK

  • Public financial support

    1,480 thou. CZK

  • Other public sources

    921 thou. CZK

  • Non public and foreign sources

    0 thou. CZK