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New tumor diagnostic kits.2

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    EUREKA - European co-operation in the sphere of applied and industrial research and development aimed at the support of multinational co-operation among industrial undertakings, research institutes and universities

  • Call for proposals

  • Main participants

    Ústav molekulární genetiky AV ČR, v. v. i.

  • Contest type

  • Contract ID

Alternative language

  • Project name in Czech

    Nová nádorová diagnostika.2

  • Annotation in Czech

    Testování protilátky TU-20, jejíž imunocytochemické parametry ukazují na vhodnost pro diagnostické účely. Reaktivita protilátky bude sledována na panelu lidských nádorů neuronálního původu a protilátka bude rovněž využita ke sledování exprese neuron-specifického tubulinu v časných fázích neuronální diferenciace teratokarcinomových buněk. Bude určena posloupnost exprese tohoto tubulinu k ostatním mikrotubulárním proteinům v průběhu diferenciace buněk P19 stimulovaných kyselinou retinovou. Tyto experimenty budou pokračovat podle původního projektu. Důraz buce kladen na testování protilátky TU-20, jejíž imunocytochemické parametry ukazují na vhodnost pro diagnostické účely. Reaktivita protilátky sledovaná na panelu lidských nádorů. Protilátka bude rovněžpoužita ke sledování exprese neuronspecifického tubulinu v časných fázích neuronální diferenciace. Budou provedeny konstrukce hybridomů z myší imunizovaných proteiny neurofilamentového tripletu.

Scientific branches

  • R&D category

  • CEP classification - main branch

    EI - Biotechnology and bionics

  • CEP - secondary branch

    EC - Immunology

  • CEP - another secondary branch

    EA - Morphology and cytology

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10601 - Cell biology<br>10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology<br>20801 - Environmental biotechnology<br>20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management<br>20803 - Environmental biotechnology related ethics<br>20901 - Industrial biotechnology<br>20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation<br>20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials<br>30102 - Immunology<br>30401 - Health-related biotechnology<br>30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)<br>30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])<br>30404 - Biomaterials (as related to medical implants, devices, sensors)<br>30405 - Medical biotechnology related ethics<br>40401 - Agricultural biotechnology and food biotechnology<br>40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming<br>40403 - Agricultural biotechnology related ethics

Solution timeline

  • Realization period - beginning

    Jan 1, 1996

  • Realization period - end

    Jan 1, 1999

  • Project status

    B - Running multi-year project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP/1997/MSM/MSM7OE/V/9:2

  • Data delivery date

Finance

  • Total approved costs

    45,480 thou. CZK

  • Public financial support

    1,500 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK