Preparation of taxol and its analoques.
Project goals
Development a procedure for small-scale production of taxanol its analogues. Preparation of a new taxol analogues.
Keywords
Public support
Provider
Ministry of Economy
Programme
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Call for proposals
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Main participants
Ústav organické chemie a biochemie AV ČR, v. v. i.
Contest type
VS - Public tender
Contract ID
—
Alternative language
Project name in Czech
Příprava taxolu a jeho analog.
Annotation in Czech
Vypracování postupů vedoucích k malotonážní výrobě taxolu a jeho analog. Příprava nových analog taxolu s protinádorovým účinkem.
Scientific branches
R&D category
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CEP classification - main branch
FR - Pharmacology and apothecary chemistry
CEP - secondary branch
CI - Industrial chemistry and chemical engineering
CEP - another secondary branch
EI - Biotechnology and bionics
20401 - Chemical engineering (plants, products)
20402 - Chemical process engineering
20801 - Environmental biotechnology
20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management
20803 - Environmental biotechnology related ethics
20901 - Industrial biotechnology
20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation
20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials
30104 - Pharmacology and pharmacy
30401 - Health-related biotechnology
30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)
30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])
30404 - Biomaterials (as related to medical implants, devices, sensors)
30405 - Medical biotechnology related ethics
40401 - Agricultural biotechnology and food biotechnology
40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming
40403 - Agricultural biotechnology related ethics
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
Vypracován semisyntetický postup výroby taxolu (využitelný i pro přípravu analog) a biotechnologický postup přípravy taxolu a jeho analog pomocí tkáňových kultur Taxus baccata, navržena a připravena nová analoga taxolu. Postup přípravy byl patentován.
Solution timeline
Realization period - beginning
Jan 1, 1997
Realization period - end
Jan 1, 2001
Project status
U - Finished project
Latest support payment
—
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP/2002/MPO/MPO2PZ/U/N/5:2
Data delivery date
Dec 19, 2002
Finance
Total approved costs
15,216 thou. CZK
Public financial support
7,716 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
7,500 thou. CZK
Basic information
Recognised costs
15 216 CZK thou.
Public support
7 716 CZK thou.
50%
Provider
Ministry of Economy
CEP
FR - Pharmacology and apothecary chemistry
Solution period
01. 01. 1997 - 01. 01. 2001