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77 (0,099s) •

Project

Lubrication mode of the human ankle joint in gait (GA103/07/0043)

) and the bearing material (articular cartilage) form a bearing system functioning in a nearly (such as osteoarthritis) alter the composition and material properties of articular cartilage to speculations and incom...

JJ - Ostatní materiály

  • 2007 - 2009
    • •
  • 348 tis. Kč
    • •
  • 348 tis. Kč
    • •
  • GA ČR
Project

The effect of the intact superficial zone of articular cartilage on lubrication and mechanical function of human synovial joints (GA103/00/0008)

is played by the heterogeneous structure of articular cartilage. In the superficial zone will be analysed with the use of biphasic mixture models for cartilage and synovial fluid. Our in the joint with the cartilage

JJ - Ostatní materiály

  • 2000 - 2002
    • •
  • 1 054 tis. Kč
    • •
  • 604 tis. Kč
    • •
  • GA ČR
Project

Populations and Degradation Fragments of Aggrecan in Human Articular Cartilage and in Synovial Fluids During Rheumatic Diseases (GA303/93/2540)

9G - 9

  • 1993 - 1995
    • •
  • 297 tis. Kč
    • •
  • 594 tis. Kč
    • •
  • GA ČR
Project

UTE-MRI in Osteoarthritis (GF25-19984L)

recently started to generate a great wealth of quantitative information on articular cartilage pathophysiology in osteoarthritis (OA). Short T2 values in the deep layer and the calcified zones of articular cartilage

Statistics and probability

  • 2025 - 2027
    • •
  • 3 715 tis. Kč
    • •
  • 3 715 tis. Kč
    • •
  • GA ČR
Project

Reconstruction of the Joint Surface using autologous osteochondral Grafts, autologous cultured Chondrocytes in Suspension and in bioactive Glass-Ceramic Material. An experimental and clinical Study. (ND6042)

The aim of the project is treatment of deep defects of knee joint cartilage. The project supposes solution of the treatment of joint cartilage. Methods:Cultivation of chondrocytes. Conductivity of bioioactive glass-ceramic materials...

FI - Traumatologie a ortopedie

  • 2000 - 2002
    • •
  • 1 469 tis. Kč
    • •
  • 1 279 tis. Kč
    • •
  • MZ
Project

An investigation of synovial fluid viscosupplementation and its impact on friction and lubrication (GA20-00483S)

Nowadays, large synovial joints often suffering from cartilage degradation and loss, represent one of the current issues because of the motion disabilities viscosupplementation. Subsequently, the effect on tribological properties of the ...

Mechanical engineering

  • 2020 - 2022
    • •
  • 4 653 tis. Kč
    • •
  • 4 653 tis. Kč
    • •
  • GA ČR
Project

Safety and efficacy evaluation of allogeneic mesenchymal stem cells derived from umbilical cord tissue in repair of cartilage defects preclinical study on animal model. (NV19-06-00355)

of articular cartilage defects in a pilot preclinical study. The cells will be seededThe current cartilage defect treatment methods are limited and there is no treatment available to ensure long-term improvement of joint f...

Biomaterials (as related to medical implants, devices, sensors)

  • 2019 - 2022
    • •
  • 14 363 tis. Kč
    • •
  • 14 363 tis. Kč
    • •
  • MZ
Project

Caspase-1 and chondrocytes integration of osteoarthritis oriented research (LUABA22019)

is associated not only with cartilage itself (e. g. joint cartilage) but also growth plates of the long bones (endochondral ossification). Cartilage, besides bone, belongs to the key structures for body support and mov...

Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])

  • 2022 - 2024
    • •
  • 1 190 tis. Kč
    • •
  • 1 190 tis. Kč
    • •
  • MŠMT
Project

Contribution of adipocyte/macrophage fatty acid-binding protein (FABP)-4 to the pathogenesis of rheumatoid arthritis and osteoarthritis (NS10620)

cartilage will be obtained from the registry of samples of the Institute of Rheumatology and hyaline cartilage. Methods of immunohistochemistry, commercially available ELISA kit: An intracellular role of increased expression of FAB...

EB - Genetika a molekulární biologie

  • 2009 - 2011
    • •
  • 4 143 tis. Kč
    • •
  • 4 143 tis. Kč
    • •
  • MZ
Project

3D printed individualised segmental joint implant optimisation of fixation to bone and biotribology of articular surface (NW25-08-00044)

, lubrication and wear mechanisms in contact with articular cartilage. The main applied...

Orthopaedics

  • 2025 - 2028
    • •
  • 19 426 tis. Kč
    • •
  • 19 426 tis. Kč
    • •
  • MZ
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