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1 741 (0,222s)

Project

Structural basis for function within the family of nitric oxide synthases (GA303/05/0336)

The family of nitric oxide synthases (inducible-iNOS; endothelial-eNOS; neuronal-nNOS) combines the unique properties of heme- and flavin-containing proteins in one polypeptide chain to achieve the, production of a small, d...

CE - Biochemie

  • 2005 - 2007
  • 3 201 tis. Kč
  • 3 201 tis. Kč
  • GA ČR
Project

The role of nitric oxide and nitric oxide synthase in the activation and maturation of pig oocytes (GA523/03/0029)

The introduction of many reproductive biotechnologies (such as cloning) into the breeding of large domestic animals has drawn attention to the meiotic maturation of oocytes and their activation. The aim of this study is to activate in vitro matured p...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2003 - 2005
  • 2 596 tis. Kč
  • 2 596 tis. Kč
  • GA ČR
Project

The role of nitric oxide and nitric oxide synthase in the acquisition of meiotic competence in pig oocytes (GP523/06/P291)

of this submitted project is to prove the possibility that nitric oxide (NO) and nitric oxide synthase (NOS) regulate the processes involved in the acquisition of meiotic competence......

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2006 - 2008
  • 1 140 tis. Kč
  • 1 140 tis. Kč
  • GA ČR
Project

Evaluation of lateralisation of nitric oxide mediator system in the hippocampus of people with schizophrenia and Alzheimer disease (NF7576)

Expression and activity of nitric oxide synthases and concentrations of L-glutamate, L-arginine, L-citrulline, nitrites/nitrates will be determined in both hippocampi of people with schizophrenia, Alzheimer disease amd mult...

ED - Fyziologie

  • 2003 - 2005
  • 5 364 tis. Kč
  • 5 257 tis. Kč
  • MZ
Project

Nitrites and Nitrates - Indicators of Nitric Oxide Synthase Activity During Pathological Strates. (IZ3141)

9F - 9

  • 1995 - 1996
  • 0 tis. Kč
  • 0 tis. Kč
  • MZ
Project

The role of interaction between nitric oxide, oxidative stress and renin-angiotensin system in the regulation of renal function and blood pressure in mice lacking gene for endothelial nitric oxide (KJB502030801)

Nitric oxide (NO) plays and important role in the regulation of cardiovascular in pathophysiology of hypertension and induces oxidative stress in the body. Reactive oxygen the role of interaction of NO, oxidative s...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2008 - 2010
  • 1 200 tis. Kč
  • 1 200 tis. Kč
  • AV ČR
Project

Study of some aspects on nitric oxide and nitric oxide synthase in hepatocytes regulation and pharmacological implications (GA305/00/1129)

Recently, it has been demonstrated that hepatocytes produce nitric oxide (NO) as the first evidence that a parenchymal cell rype could express nitric oxide synthase (iNOS or cNOS) and that NO might regulat...

FR - Farmakologie a lékárnická chemie

  • 2000 - 2002
  • 2 050 tis. Kč
  • 2 050 tis. Kč
  • GA ČR
Project

The role of nitric oxide and its derivates in the anterior eye segment under normal and pathological states (GA304/03/0419)

Nitric oxide is endogenously formed radical. The specific action of nitric oxide depends on its enzymatic sources (nitric oxide synthases, NOS) - neuronal (nNOS), endothelial (nNOS) and i...

FF - ORL, oftalmologie, stomatologie

  • 2003 - 2005
  • 4 906 tis. Kč
  • 4 906 tis. Kč
  • GA ČR
Project

Pharmacological implications of the interplay between inducible heme oxygenase/carbon monoxide and nitric oxide synthase/nitric oxide systems in liver (GA305/09/0004)

The interaction of heme oxygenase/carbon monoxide and nitric-oxide synthase/nitric oxide systems is noteworthy. Understanding the mutual regulatory mechanisms of CO and NO in hepatocyte injury will provide...

FR - Farmakologie a lékárnická chemie

  • 2009 - 2011
  • 2 190 tis. Kč
  • 2 190 tis. Kč
  • GA ČR
Project

Regulation of the Nitric Oxide during Cardiac operation with Cardiopulmonary Bypass (NR9194)

Verification if the measurement of exhaled NO is a sufficient instrument for the estimation of endothelial dysfunction after cardiac operation. Evaluation of the pharmacological myocardial preconditioning (nitrates) as a mean for aquired resistence a...

EB - Genetika a molekulární biologie

  • 2007 - 2009
  • 2 389 tis. Kč
  • 2 149 tis. Kč
  • MZ
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