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285 (0,118s) •

Project

The role of nonspecific immunity in the process of corneal graft rejection, tolerance and failure (NI7531)

The kinetics of the phenotypic markers-expression of the cells of nonspecific immunity, as the effector cells of corneal graft rejection will be investigated in the rejection process of corneal graft will be evalua...

EC - Imunologie

  • 2003 - 2005
    • •
  • 1 908 tis. Kč
    • •
  • 1 908 tis. Kč
    • •
  • MZ
Project

Tissue engineering of genetically competent corneal and conjunctival cells for subsequent grafting in human medicine (7F14156)

of corneal, limbal and conjunctival cells for potential grafting, and will investigate for grafting....

FF - ORL, oftalmologie, stomatologie

  • 2014 - 2017
    • •
  • 22 712 tis. Kč
    • •
  • 22 712 tis. Kč
    • •
  • MŠMT
Project

Local immunoregulatory mechanisms in a murine model of corneal transplantation (GA310/97/1261)

involved in corneal graft tolerance or rejection by means of detection of cytokine receptors, adhesion molecules and other immunoregulatory molecules in corneal grafts drugs. An understanding of the mechsnisms res...

FF - ORL, oftalmologie, stomatologie

  • 1997 - 1999
    • •
  • 1 279 tis. Kč
    • •
  • 1 279 tis. Kč
    • •
  • GA ČR
Project

The Role of Antigen Presentation and Immune Privilege in Rejection and Tolerance of Corneal Graft (NI6019)

Study of cellular and molecular mechanisms of immune reaction after orthotopic corneal transplantation in experimental models in mice and in patients. Characterisation of the main immunological parameters which are responsible for rejection....

FF - ORL, oftalmologie, stomatologie

  • 2000 - 2002
    • •
  • 1 634 tis. Kč
    • •
  • 1 518 tis. Kč
    • •
  • MZ
Project

Immunoregulatory role of cytokines after skin and corneal transplantation (IZ3964)

The study of cellular and molecular mechanisms of specific transplantation immunity and tolerance on the experimental models of skin grafting and orthotopical corneal allografts.......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1997 - 1999
    • •
  • 698 tis. Kč
    • •
  • 698 tis. Kč
    • •
  • MZ
Project

Identification and characterization of a novel gene causing corneal endothelial dystrophies (GPP301/12/P591)

with corneal endothelial dystrophies; an important cause of corneal grafting. It builds polymorphous corneal dystrophy, unraveling the cellular function of the novel disease the identification of novel diseasegene...

EB - Genetika a molekulární biologie

  • 2012 - 2014
    • •
  • 4 983 tis. Kč
    • •
  • 4 983 tis. Kč
    • •
  • GA ČR
Project

Cryopreservation of the corneal grafts for the transplantation purpose (NK4673)

Procured cadaverous corneal tissue will be cryopreserved.The period of storage will be practically unlimited. The methods os not usual worldwide,in Czech Republic it is totally new for corneas.......

FF - ORL, oftalmologie, stomatologie

  • 1998 - 2000
    • •
  • 811 tis. Kč
    • •
  • 772 tis. Kč
    • •
  • MZ
Project

Factors responsible for corneal graft rejection in clinical patients (IZ4185)

Cytokines and adhesion molecules involved in cornecal graft rejection in risk patients. Analys of cornecal graft survical in dependence on the surgical indication and immunosuppressive strategy used.......

FF - ORL, oftalmologie, stomatologie

  • 1997 - 1999
    • •
  • 1 248 tis. Kč
    • •
  • 1 246 tis. Kč
    • •
  • MZ
Project

Cellular and Molecular Mechanisms of Rejection and Tolerance of Orthotopic Corneal Grafts in Inbred Strains of Mice. (GA206/94/1479)

EG - Zoologie

  • 1994 - 1996
    • •
  • 380 tis. Kč
    • •
  • 560 tis. Kč
    • •
  • GA ČR
Project

Mucosal tolerance in a murine model of corneal transplantation (ME 300)

Study of cellular and molecular mechanisms of rejection and tolerance of orthotopic corneal allografts in the experimental murine model. Study of potencial of the mucosal tolerance as a strategy for suppression of the immunological rejection...

EC - Imunologie

  • 1998 - 2000
    • •
  • 2 631 tis. Kč
    • •
  • 935 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 285