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173 (0,088s)

Project

Stimuli-responsive giant vesicles for bio-applications (GN24-11194O)

-mimicking stimuli-responsive giant unilamellar polymeric vesicles (GUPVs will be studied in detail and the produced giant particles and their impact on the biological......

Polymer science

  • 2024 - 2027
  • 6 115 tis. Kč
  • 5 638 tis. Kč
  • GA ČR
Project

Advanced stimuli-responsive giant vesicles – towards the mimicking of essential cell functions (LUAUS24137)

. Specifically, giant unilamellar vesicles (GUVs) have gained popularity in bottom-up the different types of artificial cells, giant vesicles have emerged as promising......

Analytical chemistry

  • 2024 - 2027
  • 6 755 tis. Kč
  • 6 755 tis. Kč
  • MŠMT
Project

In vitro reconstitution of viral “Replication factories“ (GJ15-21030Y)

of replication factories in vitro using the biomimetic giant unilamellar vesicle (GUV) system....

CE - Biochemie

  • 2015 - 2017
  • 5 551 tis. Kč
  • 5 551 tis. Kč
  • GA ČR
Project

Bottom-up unraveling of biophysical determinants of ORP5/8 mediated lipid transport using in vitro reconstitution and model membranes (GA19-18917S)

Membrane homeostasis requires organized transport of lipids from the endoplasmic reticulum (ER) to target membrane. Oxysterol binding protein related proteins (ORPs) represent a family of lipid transfer proteins, two members of which, ORP5/8, attract...

Biochemistry and molecular biology

  • 2019 - 2021
  • 3 705 tis. Kč
  • 3 705 tis. Kč
  • GA ČR
Project

The role of hydrophobic plasma membrane interior in DOR regulation of trimeric G protein activity (GAP207/12/0919)

fluorescent analog DOR-YFP. PM will be reconstituted into model membranes, e.g. into giant unilamellar vesicles. Using cutting edge microscopy techniques (raster image correlation......

CE - Biochemie

  • 2012 - 2016
  • 9 965 tis. Kč
  • 9 965 tis. Kč
  • GA ČR
Project

Complex analyses of long term changes of the Giant Mountains tundra (SE/610/3/00)

Monitoring of the soil water regime and soil contamination by heavy metals and radon in the Giant Mountains tundra area. Development dynamics of the tundra of thevegetation and climatic changes in the Giant. Mts. tundra area. Preser...

EH - Ekologie – společenstva

  • 2000 - 2004
  • 10 539 tis. Kč
  • 9 739 tis. Kč
  • MŽP
Project

Categories and evaluation of recreational, sport and tourist activities impact related to ecosystems of central zone in Biospheric Reservation Giant Mountains (SE/630/1/03)

Documentation of tourist exploatation in specific parts of central zone in Biospheric Reservation Giant Mountains. Method ? territorial monitoring of selected ecosystem components and definition of negative impact to natural environment.......

DO - Ochrana krajinných území

  • 2003 - 2005
  • 2 300 tis. Kč
  • 2 200 tis. Kč
  • MŽP
Project

Characterization of immunomodulatory properties of extracellular vesicles derived from probiotic bacteria and their migration in the host (8J23AT019)

To verify the ability of vesicles obtained by probiotic E. coli O83 to reduce of these vesicles. 1. Aim to create E. coli O83 expressing fluorescent proteins that will subsequently be present in vesicles. Creation of E. col...

Microbiology

  • 2023 - 2024
  • 198 tis. Kč
  • 198 tis. Kč
  • MŠMT
Project

Creation of Algorithm for Surgical Treatment of Giant Congenital Pigment Naevi (NR8833)

The aim of the project is the complex evaluation of the condition of scars after repeated surgical procedures in giant pigment naevi with help of a special in patients with different types of operations and different localization of the ...

FP - Ostatní lékařské obory

  • 2006 - 2008
  • 496 tis. Kč
  • 478 tis. Kč
  • MZ
Project

Extracellular vesicles produced by Bifidobacterium as novel approach for treatment of allergy diseases (GF23-04050L)

Bifidobacterium extracellular vesicles as immunomodulators in birch pollen allergy treatment/prevention. So far, the antiallergic properties of vesicles produced by Bifidobacterium characterize the extracellular vesicles o...

Microbiology

  • 2023 - 2025
  • 5 253 tis. Kč
  • 5 253 tis. Kč
  • GA ČR
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