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7 (0,066s) •

Project

DNA and RNA detection by fluorescence in situ hybridization (FISH) (ME 132)

FD - Onkologie a hematologie

  • 1997 - 1997
    • •
  • 76 tis. Kč
    • •
  • 25 tis. Kč
    • •
  • MŠMT
Project

The occurence of hemoblastoses according to environment (RR/1694/93)

FM - Hygiena

  • 1993 - 1995
    • •
  • 146 tis. Kč
    • •
  • 222 tis. Kč
    • •
  • MŽP
Project

Integrated genomics for advanced diagnostics of non-Hodgkin lymphomas and for decifering mechanisms of drug resistence (NU23-03-00172)

Non-Hodgkin lymphomas (NHLs) represent the most common type of hematologic malignancies with incidence of 17 per 100.000 inhabitants. Current staging procedures in patients with newly diagnosed NHL are based on conventional immunohistochemistry and m...

Hematology

  • 2023 - 2026
    • •
  • 18 224 tis. Kč
    • •
  • 18 224 tis. Kč
    • •
  • MZ
Project

Sensitive method for early diagnosis and monitoring of central nervous system lymphoma using oncogenic miRNA in the cerebrospinal fluid and plasma (NV16-31586A)

Lymphoma involving CNS represents one of the most aggressive malignancies with poor prognosis and high mortality. Currently, their diagnosis suffers from low sensitivity and specificity. More powerful tools for early detection, response evaluation an...

FD - Onkologie a hematologie

  • 2016 - 2019
    • •
  • 10 493 tis. Kč
    • •
  • 9 841 tis. Kč
    • •
  • MZ
Project

Resistance to monoclonal antibody therapy at B-CLL and B-lymphomas its foundations and potential intervention strategies (NV15-33561A)

Monoclonal antibody (mAb) therapy often encounters resistance due to downmodulation of the target antigens. The exact underlying mechanisms remain unknown as well as the efficacy of newly developed mAbs. We propose to investigate the impact of severa...

FD - Onkologie a hematologie

  • 2015 - 2018
    • •
  • 9 253 tis. Kč
    • •
  • 9 253 tis. Kč
    • •
  • MZ
Project

Next generation CAR-T cells for the therapy of hematological malignancies (NU23-03-00188)

The proposed project deals with new methods of cell therapy of hematological malignancies such as AML, B-ALL and B-NHL using CAR-T T lymphocytes. The aim of the project is to build on the ongoing clinical study with CD19-specific CAR-T lymphocytes, w...

Hematology

  • 2023 - 2026
    • •
  • 13 368 tis. Kč
    • •
  • 13 368 tis. Kč
    • •
  • MZ
Project

Deciphering the pathogenesis of pediatric post-transplant lymphoproliferative disorders (NW25J-03-00076)

Post-transplant lymphoproliferative disorders (PTLD) represent a broad spectrum of lymphoid proliferations, a consequence of externally induced immunosuppression following solid organ or hematopoietic stem cell transplantation. They range from indole...

Hematology

  • 2025 - 2028
    • •
  • 6 993 tis. Kč
    • •
  • 6 993 tis. Kč
    • •
  • MZ
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