All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Filters

275 (0,089s) •

Project

Regulation of DNA replication - roles of PARP1 and p53 (GJ20-03457Y)

Replication of chromosomal DNA is a fundamental process that requires stringent. In human cells, thousands of replication origins are coordinately activated during S called replication forks. Regulation of replication

Biochemistry and molecular biology

  • 2020 - 2022
    • •
  • 7 962 tis. Kč
    • •
  • 7 962 tis. Kč
    • •
  • GA ČR
Project

Application of replication methods in pricing and hedging of financial derivatives at non-perfect market (GP402/05/P085)

replication methods. The strategy is based on setting-up of a portfolio that should have the same character as the replicated asset. Hence, we need to create a new "synthetic" asset.We can distinguish various kinds of replicati...

AH - Ekonomie

  • 2005 - 2007
    • •
  • 540 tis. Kč
    • •
  • 520 tis. Kč
    • •
  • GA ČR
Project

Replication of mammalian genome ? 4D view (KJB500390701)

Eucaryotic DNA replication ensures accurate and efficient genome duplication. Although a lot of findings about DNA replication is known, many questions about and formation of replication domains (RDs). These EM entities wer...

EA - Morfologické obory a cytologie

  • 2007 - 2009
    • •
  • 1 710 tis. Kč
    • •
  • 1 710 tis. Kč
    • •
  • AV ČR
Project

Deciphering Origins of DNA replication in genome integrity (GM22-20303M)

DNA replication is fundamental to cell proliferation, but its malfunctions can cause genome instability and trigger diseases including cancer. DNA replication initiates at replication origins by the formation of pre-rep...

Cell biology

  • 2022 - 2026
    • •
  • 24 928 tis. Kč
    • •
  • 24 928 tis. Kč
    • •
  • GA ČR
Project

Replication and chromatin organization in human cells (GA304/05/0374)

cells is arranged into replication domains of similar size. We want to test whether this arrangement is common also for diploid human fibroblasts, replication domains have structural basis and the replication and the trans...

EA - Morfologické obory a cytologie

  • 2005 - 2007
    • •
  • 4 362 tis. Kč
    • •
  • 4 362 tis. Kč
    • •
  • GA ČR
Project

Spatial and temporal characterization of DNA replication in phylogeneticaly related plant species with contrasting genome sizes (GA17-14048S)

DNA replication is a fundamental process required for growth and development of all eukaryotes. Genetic information is replicated during S phase of cell cycle under strict control to ensure that the replication occurs only ...

EB - Genetika a molekulární biologie

  • 2017 - 2021
    • •
  • 5 198 tis. Kč
    • •
  • 4 463 tis. Kč
    • •
  • GA ČR
Project

Molecular mechanisms involved in reactivation of replication forks stalled by co-transcriptional R-loops (GA22-08294S)

Transcription-replication conflicts (TRCs) associated with the formation of co replication stress and genomic instability, hallmarks of cancer. Our recent study revealed that replication fork reversal induced by R-loops is ...

Biochemistry and molecular biology

  • 2022 - 2024
    • •
  • 9 986 tis. Kč
    • •
  • 9 986 tis. Kč
    • •
  • GA ČR
Project

Exploring mechanisms of DNA replication restart upon collisions between transcription and replication complexes (GA19-07674S)

Transcription-replication collisions (TRCs) represent a significant source of genomic instability in cells experiencing DNA replication stress. Although, understanding of how a replication fork restarts DNA synthesis upon a...

Biochemistry and molecular biology

  • 2019 - 2023
    • •
  • 10 396 tis. Kč
    • •
  • 9 563 tis. Kč
    • •
  • GA ČR
Project

High-resolution spatio-temporal control of the activation mechanism of DNA replication (GC13-12317J)

Several partial mechanisms of DNA replication are to a certain depth established with many replication factors being identified. But a synthetic view on replication is still far from being reached. Biochemical analysis in v...

EA - Morfologické obory a cytologie

  • 2013 - 2016
    • •
  • 8 578 tis. Kč
    • •
  • 8 578 tis. Kč
    • •
  • GA ČR
Project

Organized biopolymer nanopatterns constructed by replication (GA22-04006S)

on doped biopolymer by replication process with potential applications in tissue sheets and nanoparticles will be optimized for consecutive replication. Selected polymer structure will be exposed to plasma or metallized. For patter...

Materials engineering

  • 2022 - 2024
    • •
  • 8 049 tis. Kč
    • •
  • 7 398 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 275