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986 (0,073s)

Project

Apoptosis of peripheral T-lymphocytes in heart transplant recipients (NI6338)

In the project submitted we plan to assess apoptosis of peripheral T-lymphocytes in relation to combined immunosuppresive therapies and acute rejection episode treatment in heart transplant recipients.......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2000 - 2002
  • 692 tis. Kč
  • 662 tis. Kč
  • MZ
Project

Activation of HIV-Specific CD8+ T Lymphocytes by IL-2 and Histamine Possible Use in Therapy? (NR9032)

Based on the results of the study with patients with hepatitis C and some oncologic diseases we will study in vitro activation of HIV-specific CD8+ T lymphocytes and IFN-gammaHistamine induces activation of cytotoxic CD8+ T...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2006 - 2008
  • 2 200 tis. Kč
  • 2 200 tis. Kč
  • MZ
Project

Advanced Immunomonitoring and Immunotherapy of Hematological and Hemato-oncological Patients (EF16_025/0007428)

of procedures for the expansion of T-lymphocytes capable of recognizing antigens of leukemic persistence of transferred multi-virus specific T-lymphocytes and their tracking in treated patients, the construction o...

Immunology

  • 2018 - 2022
  • 101 850 tis. Kč
  • 24 545 tis. Kč
  • MŠMT
Project

Chromosomal rearrangements with breakpoints in T cell receptor genes (GAP502/12/1966)

and sequencing. Percentages of γδ T-cells in peripheral blood lymphocytesT cell receptor genes (TR) are rearranged during maturation of T cells by site of chromosomes. Rearrangements of TR gene...

EB - Genetika a molekulární biologie

  • 2012 - 2014
  • 4 855 tis. Kč
  • 4 855 tis. Kč
  • GA ČR
Project

Lymphocyte subpopulatins in patients with humoral immunodeficiencies (NR7981)

T- and- B- cell surface markers, namely those known to be abnormal in patients with common variable immunodeficiency (CVID), will be analysed in patients with selective IgA deficiency, selective IgM deficiency and CVID. The results of T<...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2004 - 2006
  • 1 682 tis. Kč
  • 1 668 tis. Kč
  • MZ
Project

Cellular Immunology in Renal Transplantation Frequencies of Cytotoxic T Lymphocyte Precursors as a Prognostic Marker. (IZ2027)

9F - 9

  • 1994 - 1996
  • 434 tis. Kč
  • 661 tis. Kč
  • MZ
Project

Cellular immunology in kidney transplantation - nonrestricted versus self-restricted cytotoxic T lymphocytes (IZ4198)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1997 - 1998
  • 600 tis. Kč
  • 600 tis. Kč
  • MZ
Project

Development of peripheral gamma delta T lymhocytes in swine (GA524/07/0087)

of porcine gd T cells outside of thymus (so called peripheral gd T lymphocytes). Our preliminary results indicates that (1) peripheral gd T lymphocytes can be subdivided of peripheral CD2+CD8- gd T

EC - Imunologie

  • 2007 - 2011
  • 5 856 tis. Kč
  • 5 856 tis. Kč
  • GA ČR
Project

T-MAPs High content mapping of surface molecules in normal and disturbed development T lymphocytes, a search for diagnostic and therapeutic targets (NU20-05-00282)

Surface molecules on T-lymphocytes are crucial structures for cell-cell aim to build a dataset of normal expression of all assigned CD markers on T-cell subsets, a “T-MAP”. It will be shared on HCDM website. Next, ...

Immunology

  • 2020 - 2023
  • 9 118 tis. Kč
  • 9 118 tis. Kč
  • MZ
Project

Deciphering molecular mechanisms that drive lymphocyte morphological polarization and migration under mechanical confinement. (GJ20-24603Y)

An efficient adaptive immune response requires lymphocytes to be at the right place at the right time and depends upon lymphocytes migration and correct positioning in lymphoid tissues. According to the current paradigm, lymphoc...

Cell biology

  • 2020 - 2022
  • 7 897 tis. Kč
  • 7 897 tis. Kč
  • GA ČR
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