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42 (0,098s) •

Project

New approaches for the prevention of cardiac atrophy studies in rat model heterotopically transplanted heart (NV16-27420A)

Cardiac atrophy is the main detrimental change in fully unloaded heart during atrophy. Thus, the first aim of the present study is to evaluate whether increased heart concentrations of those FA can attenuate the process of cardiac <...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2016 - 2019
    • •
  • 9 627 tis. Kč
    • •
  • 9 627 tis. Kč
    • •
  • MZ
Project

The new insight on the pathophysiology of cardiac atrophy after implantation of left ventricular assist device translation studies to define new therapeutic targets (NU22-02-00070)

Cardiac atrophy is a critically important detrimental change in the heart-induced cardiac atrophy shows important sex-dependent differences. Thus, the first aim attenuated the course of cardiac atrophy after heterotopic hea...

Cardiac and Cardiovascular systems

  • 2022 - 2025
    • •
  • 11 218 tis. Kč
    • •
  • 11 218 tis. Kč
    • •
  • MZ
Project

Trigeminal neuralgia and experimental MR imaging influence of treatment methods on trigeminal nerve atrophy (NT11328)

The study has been designed as a prospective, blind study. We would like to verify the hypothesis that symptomatic neurovascular conflict (NVC) leads to atrophy of the trigeminal nerve on the affected side. To test this hypothesis we will us...

FH - Neurologie, neurochirurgie, neurovědy

  • 2010 - 2013
    • •
  • 3 095 tis. Kč
    • •
  • 3 095 tis. Kč
    • •
  • MZ
Project

Myopathies in the elderly over 80 with hip fracture (NG6419)

80-90 in patients over 80 with hip fracture are to be invelved.Muscle bippsy in time of surgery is to be get and investigatedy on atrophy and myopathy icluding IBM. We will use electronmicroscopy as well as antibodies against beta amyloid,be...

FE - Ostatní obory vnitřního lékařství

  • 2000 - 2002
    • •
  • 647 tis. Kč
    • •
  • 647 tis. Kč
    • •
  • MZ
Project

Molecular aspects of diagnostics and therapy of spinal muscular atrophy (1A8608)

Spinal muscular atrophy is autosomal-recessive disease caused in ca. 95% of cases by homozygous deletion of the SMN1 gene. The SMN1 gene and its SMN2 copy localise to chromosome 5q13. Differences between SMN1 and SMN2 result in different spl...

FH - Neurologie, neurochirurgie, neurovědy

  • 2005 - 2008
    • •
  • 4 414 tis. Kč
    • •
  • 4 335 tis. Kč
    • •
  • MZ
Project

Population and molecular-genetic studies of progressive retinal atrophies (PRA) in dog breeds bred in Czech Republic - methods of their detection (1QS500450578)

To elaborate molecular genetic methods for practical testing of hereditary retinal atrophy (PRA) in different dog breeds. The aim of the project is to determine homozygotes for the disease and heterozygotes - carriers of the disease, correct...

EB - Genetika a molekulární biologie

  • 2005 - 2008
    • •
  • 3 005 tis. Kč
    • •
  • 3 005 tis. Kč
    • •
  • AV ČR
Project

Helicobacter pylori infection in children and the occurence of gastric mucosa atrophy. Epidemiological study in France and in the Czech Republic (ME 443)

Medicine - pediatrics: infection caused by Helicobacter pylori, clinical symptoms, corresponding histopathological findings on gastric mucosa in children, correlation of those findings in children living in France and in the Czech Republic......

FG - Pediatrie

  • 2001 - 2001
    • •
  • 100 tis. Kč
    • •
  • 100 tis. Kč
    • •
  • MŠMT
Project

Cognitive predictors of neurodegeneration (GA16-01781S)

accurate predictor of early Alzheimer᾽s disease (AD) than atrophy of medial temporal atrophy (the first MRI scan in the first and the second in the third year) to estimate......

AN - Psychologie

  • 2016 - 2020
    • •
  • 4 734 tis. Kč
    • •
  • 4 734 tis. Kč
    • •
  • GA ČR
Project

Can administration of corticosteroids lead to structural changes in hippocampus? Prospective MRI study in human patients treated with high doses of corticosteroids. (NF6489)

Using the MRI volumetry, neuropsychological assessment and endocrinological screening, we will elucidate the relationship between long term treatment with corticosteroids and structural and functional changes of hippocampus. 20 subjects (power -95%) ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2001 - 2003
    • •
  • 2 185 tis. Kč
    • •
  • 2 172 tis. Kč
    • •
  • MZ
Project

Myokines and metabolically active molecules in the pathogenesis of idiopathic inflammatory myopathies (NU21-05-00322)

contractile activity and muscle disuse, which promote muscle atrophy, lipid accumulation, muscle atrophy- and muscle growth-related proteins will be analysed in sera as well......

Rheumatology

  • 2021 - 2025
    • •
  • 10 887 tis. Kč
    • •
  • 10 887 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 42