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2 356 (0,078s) •

Project

Research of oxime-CB(7) complexes for central nervous system penetration of quaternary acetylcholinesterase reactivator (GA18-08937S)

the biological barriers. Oximes are highly hydrophilic compounds due to their quaternary (CB[7]). Oximes@CB[7]complexes should increasingly overcome the blood-brain. In our project we will comprehensively assess the impact...

Neurosciences (including psychophysiology)

  • 2018 - 2022
    • •
  • 6 658 tis. Kč
    • •
  • 6 511 tis. Kč
    • •
  • GA ČR
Project

Development of detoxication and complex degradation methods of hazardous chemical substances and biological agents after identification of unknown substances findings (VH20182021041)

Development and verification of toxic chemical compounds complex degradation methods after findings processing. Development and verification of hazardous biological agents complex degradation methods after findings processing.......

Other natural sciences

  • 2018 - 2021
    • •
  • 8 600 tis. Kč
    • •
  • 8 600 tis. Kč
    • •
  • MV
Project

The chaperones and stress factors effect on folding and stability of the wild type and mutant cystathionine beta-synthase (CBS) (GP305/02/D167)

isto study protein folding of normal and mutant CBS in E. coli and eukaryotic on biochemical properties and oligomeric structure of the wild type and mutant CBS. Wewillexpress wild type and mutant CBS fused with green fluo...

EB - Genetika a molekulární biologie

  • 2002 - 2004
    • •
  • 580 tis. Kč
    • •
  • 580 tis. Kč
    • •
  • GA ČR
Project

When Cucurbit[n]urils Met Molecular Rods Design, Synthesis and Characterization of Supramolecular Machines in the Solid State (LTAUSA19120)

principles of CB[n]/guest recognition in the solid state, and to apply them to the design will be targeted: - Aim 1: (a) prepare CB[n]/guest complexes in the solid state (i.e. use deuterated guests or CB[n]s. - Aim 2: deco...

Organic chemistry

  • 2020 - 2022
    • •
  • 5 456 tis. Kč
    • •
  • 5 456 tis. Kč
    • •
  • MŠMT
Project

Assembly of small ribonucleoprotein particles in the cell nucleus (GA301/05/0601)

(CBs). A role for CBs in snRNP metabolism has been proposed but it is not well understood. Here we propose to test the hypothesis that CBs are the sites of U4/U6 snRNP in the cell nucleus, specifically in CBs; 2) ...

EB - Genetika a molekulární biologie

  • 2005 - 2007
    • •
  • 3 973 tis. Kč
    • •
  • 3 932 tis. Kč
    • •
  • GA ČR
Project

Transient phenomena in binary stars containing a compact object (GA205/00/P013)

a compact object (CO) (compact binaries, CB) with a special attention to their transient phenomena. CBs are highly variable objects not only in X-rays but also and in the mass-losing star. We propose to analyse the optical activity...

BN - Astronomie a nebeská mechanika, astrofyzika

  • 2000 - 2002
    • •
  • 661 tis. Kč
    • •
  • 421 tis. Kč
    • •
  • GA ČR
Project

LIBRI CIVITATIS - the documentation and editorial preparation of town in the Czech II. (GA13-09254S)

)and associated the research activities in the field of city books (CB).Within the project, the outdated list of CB to 1526 was revised and added to 1620. It was developed an on-line db of CB,with their descriptions in sel...

AB - Dějiny

  • 2013 - 2017
    • •
  • 3 255 tis. Kč
    • •
  • 3 255 tis. Kč
    • •
  • GA ČR
Project

Activity of Cathepsine B in Patient with Bladder Cancer (NT11415)

Cathepsin B (CB) is a thiol-dependent protease that - under normal conditions - may be found in lysosomes of mammal cells. CB is studied not only for its place its role as a diagnostic and prognostic marker by analysis of CB

FP - Ostatní lékařské obory

  • 2010 - 2014
    • •
  • 4 370 tis. Kč
    • •
  • 4 370 tis. Kč
    • •
  • MZ
Project

Sensory Research Centre in Prague and Brewhouse for research and development - sustainability and development (LO1312)

for formulating the sensory properties of Czech beer (CB) in the context of raw materials and technological production processes. Advanced analytical and sensory maps of CB and raw and undesirable flavor compounds by these...

GM - Potravinářství

  • 2014 - 2019
    • •
  • 20 978 tis. Kč
    • •
  • 9 198 tis. Kč
    • •
  • MŠMT
Project

Mutation in cystathionine ß-synthase gene effects on enzyme function in vitro and S-adenosylmethionine metabolism in vivo. (GA302/97/0476)

arterial disease,respectivly.Complete cystathionine beta-synthase(CBS) deficiency pathogenic mechanisms in patients with CBS deficiency:1. We intend to carry out patients with CBS deficiency exhibit any abnormalities both ...

FG - Pediatrie

  • 1997 - 1999
    • •
  • 2 673 tis. Kč
    • •
  • 2 673 tis. Kč
    • •
  • GA ČR
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