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104 (0,077s) •

Project

The effects of deport steroids in preventing the occurrence of postoperative fibrosis. (NF6559)

adhessions. Checking the belief that not every pacient with epidural fibrosis hasControl of new possibilities in the prevention of postoperative epidural fibrosis with the help of the application of materials prev...

FH - Neurologie, neurochirurgie, neurovědy

  • 2001 - 2003
    • •
  • 532 tis. Kč
    • •
  • 532 tis. Kč
    • •
  • MZ
Project

Peroperative application of depot steroid in decompressive surgical treatment for degenerative lumbar spine disease. (NR8848)

Comparison of postoperative course in two groups of patients treated by decompressive surgery for degenerative involvement of lumbar spine. Follow-up of early and late postoperative clinical course aimed at prevention of epidural fibrosi...

FH - Neurologie, neurochirurgie, neurovědy

  • 2006 - 2008
    • •
  • 939 tis. Kč
    • •
  • 939 tis. Kč
    • •
  • MZ
Project

Effects of perioperative opioid analgesia on circulating tumor cells in colorectal cancer multicenter randomized clinical trial (NV18-03-00470)

CTCs presence and shortens disease-free survival. Also epidural PA may influence CR comparing effects of epidural, morphine- and piritramide-based PA on CTCs presence......

Oncology

  • 2018 - 2022
    • •
  • 15 056 tis. Kč
    • •
  • 14 993 tis. Kč
    • •
  • MZ
Project

Hepatic stellate cells scintigraphy as a marker of early liver fibrosis (NR7833)

Isotope-labeled compounds will be synthetized for scintigraphical detection of hepatic stellate cells transformation in the early stages of liver fibrosis. Compound feasibility will be tested on liver fibrosis animal models.......

FE - Ostatní obory vnitřního lékařství

  • 2004 - 2006
    • •
  • 1 895 tis. Kč
    • •
  • 1 827 tis. Kč
    • •
  • MZ
Project

Improvement of care for patients with cystic fibrosis by early and efficient diagnosis via two-tier neonatal screening programme (1A8236)

The aim is to assess the efectivity of newborn screening for cystic fibrosis in the condition of Czech Republic....

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2006
    • •
  • 6 193 tis. Kč
    • •
  • 6 182 tis. Kč
    • •
  • MZ
Project

Analysis of Extracellular Niche in Mouse Models of Liver Fibrosis (GA18-02699S)

Liver fibrosis is excessive scarring process resulting from chronic insults pathology with high mortality. The major hallmark of liver fibrosis is deposition the development and resolution of two different types of liver fibrosi...

Cell biology

  • 2018 - 2022
    • •
  • 8 694 tis. Kč
    • •
  • 7 813 tis. Kč
    • •
  • GA ČR
Project

Impact of direct endoglin modulation on the development of major complications of metabolic syndrome atherogenesis and non-alcoholic steatohepatitis (GA22-14961S)

dysfunction, atherogenesis, liver fibrosis, and non-alcoholic steatohepatitis (NASH or alleviate atherogenesis, liver fibrosis, and NASH. We will focus on changes in Eng of Eng on fibrosis will be studied in a mouse model ...

Pharmacology and pharmacy

  • 2022 - 2024
    • •
  • 8 954 tis. Kč
    • •
  • 8 954 tis. Kč
    • •
  • GA ČR
Project

Identification of markers of interstitial fibrosis in asymptomatic hydronephrosis in infants (NK6605)

The aim of the proposed project is to to study the ACE serum and urinary activity and urinary excretion of TGF beta 1 in relationship to the degree of interstitial fibrosis in infants with asymptomatic hydronephrosis......

FG - Pediatrie

  • 2001 - 2003
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  • 1 335 tis. Kč
    • •
  • 1 289 tis. Kč
    • •
  • MZ
Project

Impact of combined adrenergic blocade on the outcome of high-risk patients udergoing major abdominal or thoracic surgery (ND6629)

Prospective randomized study assess two different ways of haemodynamic management in high-risk surgical patients during perioperative and postoperative period and compare them to current standard of our care in terms of mortality and morbidity.......

FJ - Chirurgie včetně transplantologie

  • 2001 - 2003
    • •
  • 2 507 tis. Kč
    • •
  • 2 382 tis. Kč
    • •
  • MZ
Project

Genetic determinants of interstitial fibrosis and coronary microvascular remodelation (LH11049)

We will use histomorphometric analyses to determine the presence and extent of coronary microvascular remodeling and myocardial fibrosis in the BXH/HXB recombinant inbred strains derived from the spontaneously hypertensive rats (SHR) and Bro...

EB - Genetika a molekulární biologie

  • 2011 - 2014
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  • 3 564 tis. Kč
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  • 3 564 tis. Kč
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  • MŠMT
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