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7 (0,133s)

Project

New tools of label-free electrochemical analysis of protein interactions with nucleic acids and proteins (GA18-18154S)

by a constant current chronopotentiometry at bare or thiol-modified electrodes containing of proteins, important in biomedicine and oncology, by combination of chronopotentiometry......

Biophysics

  • 2018 - 2021
  • 3 613 tis. Kč
  • 3 433 tis. Kč
  • GA ČR
Project

New approaches in electrochemical analysis of nucleic acids and oligonucleotides aimed at a ultrasensitive microdetection of DNA and DNA hybridization. (IAA100040602)

The proposed research is dealing with structure, determination and interactions of oligodeoxynucleotides in solution and at surfaces. New important information should be obtained about oligonucleotides and nucleic acids at electrically charged surfac...

BO - Biofyzika

  • 2006 - 2008
  • 1 884 tis. Kč
  • 1 884 tis. Kč
  • AV ČR
Project

New tools for research and diagnostics of diseases. Microfluidic reactors and electrochemistry for analysis of proteins and their glycosylation. (GA15-15479S)

chronopotentiometry and thiol-modified mercury or solid amalgam electrodes. Using high current...

CG - Elektrochemie

  • 2015 - 2017
  • 6 400 tis. Kč
  • 6 315 tis. Kč
  • GA ČR
Project

Chemical modified solid electrodes in electrochemical analysis of the nucleic acids and their components (KJB4004305)

or chronopotentiometry will be investigated....

CG - Elektrochemie

  • 2003 - 2005
  • 1 680 tis. Kč
  • 1 420 tis. Kč
  • AV ČR
Project

Study of binding of platinum cytostatics to DNA structure; Influence of metallothionein (IAA401990701)

Suggestion of biosensor for determination of platinum, which could be applied to direct detection of platinum therapeutic concentration in human body liquids of tumour diseases patients, is an assumed contribution of this project for clinical practis...

CG - Elektrochemie

  • 2007 - 2011
  • 2 904 tis. Kč
  • 2 904 tis. Kč
  • AV ČR
Project

Emerging roles for the proteins of Anterior Gradient family in cancer development (GA13-00956S)

The exact functions and regulation of Anterior Gradient protein family are poorly understood, but current data identify AGR2 and AGR3 as clinically relevant factors modulating the behavior and response of many cancers in both hormone-dependent and ho...

FD - Onkologie a hematologie

  • 2013 - 2017
  • 10 173 tis. Kč
  • 10 173 tis. Kč
  • GA ČR
Project

New tools for research and diagnostics of glycans and glycoproteins using electrochemical analysis and chemical modification. (GA22-26590S)

The proposed project responds to the needs of present progress in the analysis of glycans and glycoproteins, as important biomarkers of various diseases. In the project, we propose new approaches to the study of glycans and glycoproteins, based on th...

Analytical chemistry

  • 2022 - 2024
  • 3 389 tis. Kč
  • 3 389 tis. Kč
  • GA ČR
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