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6 (0,069s)

Project

Screening of mutations in the duplicated region of the PKD1 gene from families with autosomal dominant polycystic kidney disease (NR9427)

Analysis of mutations in duplicated region of the PKD1 gene in selected families with ADPKD by LR-PCR , screening methods (SSCP,HA,DGGE) and following sequencing of positive fragments.......

EB - Genetika a molekulární biologie

  • 2007 - 2010
  • 4 789 tis. Kč
  • 4 669 tis. Kč
  • MZ
Project

Screening of mutations in the non-duplicated region of the PKD1 gene from families with autosomal dominant polycystic kidney disease (NE7633)

Analysis of mutations in non-duplicated region of the PKD1 gene in selected families with ADPKD by screening methods (SSCP,HA,DGGE) and following sequencing of positive fragments.......

EB - Genetika a molekulární biologie

  • 2003 - 2005
  • 3 439 tis. Kč
  • 3 364 tis. Kč
  • MZ
Project

Screening of mutations in the PKD2 gene from families with autosomal dominant polycystic kidney disease. (NE5996)

Analysis of mutations in PKD2 gene in selected families with ADPKD by screening methods (SSCP,HA,DGGE) and following sequenation of positive fragments. Analysis of mutations in PKD2 gene is the only temporary available method in diferentiald...

FE - Ostatní obory vnitřního lékařství

  • 2000 - 2002
  • 3 422 tis. Kč
  • 3 420 tis. Kč
  • MZ
Project

Management of hypertension,proteinuria an progression of autosomal dominant polycystic kindney disease in children. (NE6295)

Treatment of hypertension by ACEI in patients with ADPKD is planed.The influence of this tratment on blood pressure,glomerular filtration rate,proteinuria and tubular function will be investigated. The proposers want to try to infuence the u...

FG - Pediatrie

  • 2000 - 2002
  • 867 tis. Kč
  • 867 tis. Kč
  • MZ
Project

Role of fibrosis and vascular changes in pathogenesis of autosomal dominant polycystic kidney disease (ADPKD). (IZ4047)

Study s target is to unclear role of vascular a fibrotic changes,and underlying processes,in patiens with polycystic kidney disease and in a model of cystic tubular dilatation developped in a chick embryo by modulation of blood supply.......

FE - Ostatní obory vnitřního lékařství

  • 1997 - 1999
  • 1 702 tis. Kč
  • 1 410 tis. Kč
  • MZ
Project

Multigenic etiology in hereditary kidney disorders in children polycystic kidney disease and atypical HUS (NT11457)

gene in patients with ARPKD and ADPKD and establish HNF1B gene as a modifier gene...

EB - Genetika a molekulární biologie

  • 2010 - 2014
  • 4 792 tis. Kč
  • 4 792 tis. Kč
  • MZ
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