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4 939 (0,114s)

Project

New paradigm for functional contrast agent for 31P magnetic resonance imaging (NU20-08-00095)

contrast in response to external biochemical changes. The contrast agents act solely as T1 contrast agents for 1H MR to provide anatomical information. As the 31P signal phosphorus-containing

Biophysics

  • 2020 - 2023
  • 12 608 tis. Kč
  • 12 608 tis. Kč
  • MZ
Project

Synthesis and screening of selective probes for magnetic resonance imaging (GJ17-22834Y)

Project is focused on preparation of responsive contrast agents based of potential contrast agents for testing. Original molecular design will allow preparation and testing of a new type of responsive<...

CC - Organická chemie

  • 2017 - 2021
  • 5 331 tis. Kč
  • 5 331 tis. Kč
  • GA ČR
Project

Combined contrast agents for molecular MR imaging (KAN201110651)

utilizations. Their suitability as cell positive contrast agents, especially based with dendrimers will be used for formation of the combined contrast agents, that will giveboth positive and negative contrast<...

CA - Anorganická chemie

  • 2006 - 2010
  • 38 361 tis. Kč
  • 32 126 tis. Kč
  • AV ČR
Project

Novel Metal-Free Contrast Agents for 1H Magnetic Resonance and Optical Imaging (NW24-08-00144)

the limitations of conventional metal-based contrast agents, such as gadolinium chelates combination of stable Organic Radical Contrast Agents (ORCAs) and advanced biocompatible polymers, our goal is to create MRI...

Medicinal chemistry

  • 2024 - 2027
  • 13 318 tis. Kč
  • 13 318 tis. Kč
  • MZ
Project

Properties of Nanopowders Prepared by a Pulsed Electron Beam Method in a Low-Pressure Gas (GC21-31852J)

nanoparticles, namely CeO2 for radiation oncology, Gd2O3 and MnO as contrast agents, ZnO and TiO2 as antitumor agents, Al2O3 and AgO as antibacterial agents, and Fe3O4/γFe2O3 on recent findings of serious toxicity...

Materials engineering

  • 2021 - 2023
  • 5 117 tis. Kč
  • 5 117 tis. Kč
  • GA ČR
Project

Paramagnetic switches in polymer contrast agents for 19F and 31P magnetic resonance The new paradigm in noninvasive cancer functional imaging (LTC19032)

The aim of this project is to develop a conceptually new class of cancer-aimed biodegradable phosphorus or fluorine-containing polymer contrast agents for 1H / 31P or 1H / 19F magnetic resonance (MR) providing both anatomical (1H M...

Polymer science

  • 2019 - 2022
  • 4 920 tis. Kč
  • 4 920 tis. Kč
  • MŠMT
Project

Detection of the dynamic of gadolinium retention in the brain after application of MR contrast agents using alteration of T1 and T2 relaxation times. Prospective study. (NV18-04-00457)

of MR contrast agents is a important phenomenon. Its pathophysiology and clinical contrast agents, a certain plateau is reached or relaxation times are prolonged will also be studied, however contrast

Clinical neurology

  • 2018 - 2022
  • 2 891 tis. Kč
  • 2 891 tis. Kč
  • MZ
Project

Cellular contrast agents for MR imaging (GA309/06/1594)

image is lower than the cell size, the cells can be visualized by contrast agents of this project is development and usage of new contrast agents for MR imaging based on iron......

FH - Neurologie, neurochirurgie, neurovědy

  • 2006 - 2008
  • 4 013 tis. Kč
  • 4 013 tis. Kč
  • GA ČR
Project

Self-assembled polymeric nanostructures as bimodal magnetic resonance ultrasound contrast agents for imaging (GA16-03156S)

Development of bimodal 1-H and 19-F magnetic resonance imaging (MRI) - ultrasonic the contrast agents for the diagnostics of solid tumors or monitoring cell polymer nanoparticles possess favorable properties as contrast

BO - Biofyzika

  • 2016 - 2018
  • 8 971 tis. Kč
  • 8 461 tis. Kč
  • GA ČR
Project

Complexes of fluorinated ligands with paramagnetic metal ions for 19F MRI and bimodal 1H/19F contrast agents (GA22-34083S)

MRI is common imaging methods in medicine. To improve resolution, contrast agents (MRI CAs) based mainly on complexes of Gd(III) are often used. Under some conditions, these MRI CAs can be toxic and, therefore, alternative CAs utili...

Inorganic and nuclear chemistry

  • 2022 - 2024
  • 5 991 tis. Kč
  • 5 991 tis. Kč
  • GA ČR
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