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3 862 (0,181s) •

Project

How lipid asymmetry influences membrane protein function (GF25-19982L)

, characterized by distinct lipid compositions in their two leaflets, most studies use, elucidating the structural and dynamical properties of lipids in asymmetric membranes and their interactions with integral membrane pro...

Biophysics

  • 2025 - 2027
    • •
  • 5 318 tis. Kč
    • •
  • 5 318 tis. Kč
    • •
  • GA ČR
Project

Peptide Killers of Bacteria (LL2007)

We will develop a method for the targeting of peptides to membranes with specific lipid composition and determine key peptide properties for membrane translocation and pore formation. The designed peptides will be experimentally tes...

Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

  • 2020 - 2021
    • •
  • 13 476 tis. Kč
    • •
  • 13 476 tis. Kč
    • •
  • MŠMT
Project

New metabolic pathways of lipid trafficking (LUAUS24040)

synthesis in endosomes, their composition and role in endosome sorting. 1.3 Define the composition of lipid cargo directed to extracellular vesicles by labeling lipids quantitative analysis of intra- and inter-cel...

Biochemistry and molecular biology

  • 2024 - 2027
    • •
  • 10 122 tis. Kč
    • •
  • 10 122 tis. Kč
    • •
  • MŠMT
Project

Structural and functional analysis of regulation of the lipid-transport protein ORP8 (GF21-27735K)

maintains proper lipid composition of intracellular membranes. As such it mustLipids transport between various membranous intracellular organelles family specialized in transporting lipids. Oxysterol-binding prote...

Biochemistry and molecular biology

  • 2021 - 2023
    • •
  • 4 220 tis. Kč
    • •
  • 3 260 tis. Kč
    • •
  • GA ČR
Project

Changes of lipid metabolism and composition during colorectal carcinogenesis - the effects of butyrate and polyunsaturated fatty acids (GAP301/11/1730)

of cellular lipid structure and composition and investigate changes of lipid transporter proteins (FAT/CD36, caveolin-1), accumulation of cytoplasmic lipid droplets lipid alterations and influence the eff...

EB - Genetika a molekulární biologie

  • 2011 - 2013
    • •
  • 6 874 tis. Kč
    • •
  • 6 874 tis. Kč
    • •
  • GA ČR
Project

PRESENTATION OF THE PROJECT "CHANGES IN LIPID COMPOSITION OF BRAIN IN ALZHEIMER'S DISEASE" (PG97216)

FH - Neurologie, neurochirurgie, neurovědy

  • 1997 - 1997
    • •
  • 94 tis. Kč
    • •
  • 47 tis. Kč
    • •
  • MŠMT
Project

Lipids of bumblebees and their role in the biosynthesis of pheromonal components (IAA4055403)

components of the male marking pheromone. Composition of lipids in different species will be determined. Storage form of lipids in the fat body [triacylglycerols, diacylglycerolsStorage, mobilisation, transport, and metabo...

CC - Organická chemie

  • 2004 - 2008
    • •
  • 2 650 tis. Kč
    • •
  • 2 650 tis. Kč
    • •
  • AV ČR
Project

Effects of different fatty acid composition in home parenteral nutrition formula on lipid metabolism and inflammatory markers (NT13236)

The project should contribute to optimisation of FA representation in the lipid, Lipoplus ®, Smof lipid ®). After 6 weeks in each cycle an increased dose of fish oil indicators of tolerance will be monitored. The spectrum of FA in b...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2012 - 2015
    • •
  • 6 024 tis. Kč
    • •
  • 6 024 tis. Kč
    • •
  • MZ
Project

Influence of cadmium and mercury compounds and fish lipids on cell lipid metabolism, oxidative stress and cell viability (GA13-01543S)

of cancer It remains to evaluate if Cd2+ and Hg2+ also influence lipid composition composition analyses in different fractions of the cells, gene expression analyses on cell viability and correlate this with our results o...

GM - Potravinářství

  • 2013 - 2017
    • •
  • 5 190 tis. Kč
    • •
  • 5 190 tis. Kč
    • •
  • GA ČR
Project

Deciphering the molecular mechanism of lipid-induced topological switching of membrane proteins (LUAUS25113)

to the changes of its lipid environment. It is widely accepted that membrane proteins always in the membrane in response to changes in the lipid environment or charge of their extracellular domain. The influence of lipid ...

Biophysics

  • 2025 - 2028
    • •
  • 4 924 tis. Kč
    • •
  • 4 924 tis. Kč
    • •
  • MŠMT
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