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9 232 (0,131s)

Project

Interplay and regulation of processes essential to yeast biofilm formation Role of environmental factors and specific regulators (GA19-11384S)

-specific processes and aims to discover whether these processes are regulated will identify functions of specific regulators and environmental factors in switching on/off available techniques, are vital tools for ...

Microbiology

  • 2019 - 2022
  • 8 867 tis. Kč
  • 8 680 tis. Kč
  • GA ČR
Project

Expression of lincomycin biosynthetic gene cluster and its regulation (GA204/05/0616)

and resulting antibiotic production are the expected results. Information on pathway-specific regulators and organization of transcription units is indispensable for and partial knowledge of its pathway, putative ...

EB - Genetika a molekulární biologie

  • 2005 - 2007
  • 2 466 tis. Kč
  • 2 466 tis. Kč
  • GA ČR
Project

Metabolic pathways and regulatory mechanisms responsible for vitality and longevity of cells specifically localized within yeast colonies (GA15-08225S)

molecular mechanisms and regulations involved in formation and development of this colony subpopulation including regulators of conserved pathways such as TORC1, and will identify metabolic pathways and processes ...

EB - Genetika a molekulární biologie

  • 2015 - 2017
  • 10 430 tis. Kč
  • 10 430 tis. Kč
  • GA ČR
Project

A continuum model for tumour suppressor mechanism orchestrated by the Hippo signalling pathway. (GP14-21095P)

metabolism. Since Hippo/MST protein activity seems to be regulated by specific products for the Hippo/MST activation. Our data can help to understand how Hippo pathway regulatesHippo signalling pathway re...

EB - Genetika a molekulární biologie

  • 2014 - 2016
  • 2 448 tis. Kč
  • 2 448 tis. Kč
  • GA ČR
Project

Mysteries of nitrogen regulation in yeast populations Functions of TORC1 and other nutrient sensing pathways (LTAUSA18162)

is to elucidate the mechanisms of alternative regulatory pathways responding to changes in nitrogen metabolites, determine how these nitrogen-responsive pathways mutually" in these regulations in eukaryotes is the conserve...

Human genetics

  • 2019 - 2022
  • 11 301 tis. Kč
  • 11 301 tis. Kč
  • MŠMT
Project

Gp130 receptor-mediated differentiation of ES cells (GA301/08/0717)

therapies andregenerative medicine. Here, the gp130 receptor-mediated signalling pathway of the IL-6 cytokine family and their role in the regulation of ES cell differentiation will be studied. This pathway is known to sup...

FP - Ostatní lékařské obory

  • 2008 - 2010
  • 2 712 tis. Kč
  • 2 712 tis. Kč
  • GA ČR
Project

Gibberellin biosynthesis and signal transduction – identification of novel targets for plant growth regulation (GA18-10349S)

regulated dioxygenases that catalyse the later steps of the biosynthetic pathwayThe gibberellin (GA) plant hormones regulate numerous physiological processes lack specificity and can produce unwanted side-effects....

Plant sciences, botany

  • 2018 - 2022
  • 8 803 tis. Kč
  • 8 495 tis. Kč
  • GA ČR
Project

Study of the functions of endocytosis and intracellular trafficking regulators in Wnt signalling (GAP305/10/0507)

pathways have emerged as important regulators of Wnt signalling. However, an in-depthThe Wnt signalling pathway is required during a wide variety of developmental processes, including body axis specification, stem...

EB - Genetika a molekulární biologie

  • 2010 - 2014
  • 4 083 tis. Kč
  • 4 083 tis. Kč
  • GA ČR
Project

Role of hypoxia and intracellular redox status disbalance in a regulation of cell selfrenewal and differentiation (LD11015)

directed signaling pathways. The cell fate thus may be modulated through specific inhibitors targeted to components of selected signaling pathways and/or through drugs, sensitivity of the selected signaling pathways

ED - Fyziologie

  • 2011 - 2013
  • 1 915 tis. Kč
  • 1 915 tis. Kč
  • MŠMT
Project

Understanding cell compartment and liquid phase restricted functions of Dishevelled (GA22-25365S)

The project will address how Dishevelled (DVL), the key signaling regulator in the Wnt pathway, achieves its multitude of functions. The basis of the project are the mechanisms that regulate liquid-liquid phase separation (...

Cell biology

  • 2022 - 2024
  • 13 338 tis. Kč
  • 13 326 tis. Kč
  • GA ČR
  • 1 - 10 out of 9 232