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23 (0,146s) •

Project

Radiolabelled neuropeptides for cancer diagnosis and treatment (GAP304/10/1738)

Radiolabelled neuropeptides could be considered as future agents for diagnostic imaging and therapy of cancers and their metastasis because neuropeptide receptors behavior of new radiolabeled receptor-specific peptides (derivatives ...

FR - Farmakologie a lékárnická chemie

  • 2010 - 2012
    • •
  • 2 190 tis. Kč
    • •
  • 2 190 tis. Kč
    • •
  • GA ČR
Project

Study of pharmacokinetics and biodistribution of radiolabelled biologically active peptides in laboratory animals (OC B12.001)

The aim of this project is to receive new knowledge about preparation and biological behaviour of the radiolabelled receptor-specific peptides with the intention to find new radiodiagnostics or radiotherapeutics of tumours under endocrine co...

FR - Farmakologie a lékárnická chemie

  • 2001 - 2004
    • •
  • 5 106 tis. Kč
    • •
  • 1 752 tis. Kč
    • •
  • MŠMT
Project

Receptor-specific radiopharmaceuticals for imaging and therapy of cancers (GA305/07/0535)

Receptor imaging with radiolabelled receptor-specific peptides has proven to be a valuable method for the visualization of neuroendocrine tumours and their metastasis. A new application is the use of these peptides for receptor-mediated ther...

FR - Farmakologie a lékárnická chemie

  • 2007 - 2009
    • •
  • 2 670 tis. Kč
    • •
  • 2 670 tis. Kč
    • •
  • GA ČR
Project

Biodegradation of Pesticides (ME 318)

Using radiotracer methodology, the isoproturone biodegradation in Quarternary gravel is analyzed to assess its ecotoxicity. Selected isolates of soil microorganisms are used in combination with laboratory columns under different conditions or lysimet...

DK - Kontaminace a dekontaminace půdy včetně pesticidů

  • 1998 - 2002
    • •
  • 1 235 tis. Kč
    • •
  • 277 tis. Kč
    • •
  • MŠMT
Project

Effect of amino acids hormones on protein metabolism in catabolic illness (NB6793)

Investigation of the pathogenesis and treatment of protein wasting in catabolic illness. Experimental studies using radiolabeled compounds on laboratory rats.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2001 - 2003
    • •
  • 1 695 tis. Kč
    • •
  • 1 415 tis. Kč
    • •
  • MZ
Project

Cyclotron preparation of Tb-161 as an altervative to Lu-177 for therapy in nuclear medicine (TJ04000138)

The main aim of the project is to obtain pure Tb-161 and, if possible, to change the way of its preparation from a nuclear reactor to cyclotron for radiolabelling purposes of chosen compounds for nuclear medicine. This includes excitation wi...

Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

  • 2020 - 2022
    • •
  • 6 662 tis. Kč
    • •
  • 5 661 tis. Kč
    • •
  • TA ČR
Project

Possibility of modification of nephrotoxicity of radiopharmaceuticals from the group of somatostatin analogs (NR9208)

The targeted radionuclide therapy using radiolabelled somatostatin receptor-specific peptides is a used and developing method to treat some type of tumours. However, undesirable retention of radioactivity in the kidney with subsequent of

FR - Farmakologie a lékárnická chemie

  • 2007 - 2009
    • •
  • 2 229 tis. Kč
    • •
  • 2 229 tis. Kč
    • •
  • MZ
Project

Mechanism of action of selected synthetic analogs of insect peptide with high oostatic activities (GA203/06/1272)

theirmetabolites by radio-HPLC/MS, and measurement of ecdysone levels. The radiolabelling...

CC - Organická chemie

  • 2006 - 2008
    • •
  • 2 170 tis. Kč
    • •
  • 2 170 tis. Kč
    • •
  • GA ČR
Project

Biodegradation and translocation of juvenogens as termite caste differentiation regulators and associated environmental protection (GA203/05/2146)

and ecotoxicity of juvenogens and their degradation products. Radiolabeling of the studied...

CB - Analytická chemie, separace

  • 2005 - 2007
    • •
  • 3 998 tis. Kč
    • •
  • 3 998 tis. Kč
    • •
  • GA ČR
Project

Magnetic or 90Y-radiolabeled light-upconverting nanoparticles for photodynamic therapy or radiotherapy of tumors (GA15-01897S)

With rapid development of nanomedicine, new polymer-coated upconverting nanoparticles (UCNs) are needed for light-controlled drug release in treatment of cancer. Aim of the project is to design and optimize proper organic or inorganic polymer-modifie...

BO - Biofyzika

  • 2015 - 2017
    • •
  • 7 632 tis. Kč
    • •
  • 7 632 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 23