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1 007 (0,155s) •

Project

IMMUNO - INFLAMMATORY MECHANISMS IN PATHOGENESIS OF NASAL POLYPOSIS (NR8517)

Activated mucosal immune cells in nasal polyps. Role of growth factors, cytokines and chemokines in NP. Innate immune mechanisms in pathogensis of nasal polyposis. Role of non-endothelial expression of ICAMs in nasal polypo...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2005 - 2007
    • •
  • 2 279 tis. Kč
    • •
  • 2 279 tis. Kč
    • •
  • MZ
Project

Innate immunity in human type 1 diabetes Revealing a new role for dendritic cells, monocytes and neutrophils involved in the development of T1D (NV16-32838A)

. The involvement of adaptive immunity was clearly demonstrated. The role of innate immunity players in evolvement and maintenance of peripheral immune tolerance. Studies in animal models demonstrated the interacti...

EC - Imunologie

  • 2016 - 2019
    • •
  • 13 213 tis. Kč
    • •
  • 13 213 tis. Kč
    • •
  • MZ
Project

Role of innate immunity in the pathogenesis of type I diabetes (GAP302/10/1679)

is is known about the role of innate immunity in disease onset and progression.Recently a study of innate immunity in a cohort of children with T1D, at onset and during and their respective function.Microarray ana...

EC - Imunologie

  • 2010 - 2014
    • •
  • 7 935 tis. Kč
    • •
  • 7 935 tis. Kč
    • •
  • GA ČR
Project

Identification and mapping of genes as a ground of function genomic analysis of innate immunity response in the horses (GP523/03/P089)

of innate immunity response is macrophage - antigen phagocyting, processing influencing immunity response (candidate genes), mapping and analysis of expression of macrophage activity and control genes as a ground of functi...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2003 - 2005
    • •
  • 652 tis. Kč
    • •
  • 652 tis. Kč
    • •
  • GA ČR
Project

Characterization of selected innate immunity genes in domestic and wild felids (GF21-28637L)

in felids. Here, innate immunity genes will be identified by hybridization capture. The results will also be used for characterizing the extent of genetic diversity in innate immunity genes of two endangered felid...

Veterinary science

  • 2021 - 2023
    • •
  • 4 893 tis. Kč
    • •
  • 4 893 tis. Kč
    • •
  • GA ČR
Project

Genetic resistance to infectious disease use of genomics for dissecting mechanisms of innate immunity in the horse (GA523/02/1526)

will be investigated. Genetic resistance to intracellular bacteria and mechanisms of innate immunity were selected as models. Approaches of strucutral and functional genomics will be applied for this purpose. Based on the contempor...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2002 - 2004
    • •
  • 3 640 tis. Kč
    • •
  • 3 640 tis. Kč
    • •
  • GA ČR
Project

Molecular epidemiology of emerging infectious diseases. (MEB021130)

The aim of the project is to analyse the relationships between the genetic variation of innate immunity genes and sensitivity to pathogens of wild rodents. Studied pathogens are transmissible among animals and human and may cause da...

EC - Imunologie

  • 2011 - 2011
    • •
  • 66 tis. Kč
    • •
  • 66 tis. Kč
    • •
  • MŠMT
Project

The role of innate immunity in the pathogenesis of the diabetes mellitus type 1 (NT11407)

. The involvement of T and B cells mediated adaptive immunity was clearly demonstrated. Much less is known about innate immunity in the disease onset and progression. Recent activation. Thus, we propose a study of innat...

FG - Pediatrie

  • 2010 - 2014
    • •
  • 7 156 tis. Kč
    • •
  • 7 156 tis. Kč
    • •
  • MZ
Project

ThymIA Thymic dysfunction and its role in Innate and Adaptive immunity (NU23-05-00097)

dysfunctions and their impact on innate and adaptive immunity. It builds on previous works also towards the complex network of innate immunity, in particular monocytes and dendritic cells. The project further aims...

Immunology

  • 2023 - 2026
    • •
  • 10 100 tis. Kč
    • •
  • 10 100 tis. Kč
    • •
  • MZ
Project

Mitochondrial and nuclear DNA cross-talk and its impact on metabolic phenotype and innate immunity (GA19-10354S)

studies suggested that mtDNA may trigger innate immune response probably due to its are consequences of systemic inflammation caused by activation of immune system in spontaneous immune response or after metaboli...

Endocrinology and metabolism (including diabetes, hormones)

  • 2019 - 2022
    • •
  • 6 634 tis. Kč
    • •
  • 6 580 tis. Kč
    • •
  • GA ČR
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