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1 420 (0,134s)

Project

*Construction of simple dipstickfor organophosphates assay (FR-TI1/541)

of cholinesterases. Organophosphates and carbamates will be assayed during project solution immobilization and optimization of enzyme activity as marker of organophosphate presence following. Approachability of developed dipsticks ...

CB - Analytická chemie, separace

  • 2009 - 2011
  • 10 576 tis. Kč
  • 6 599 tis. Kč
  • MPO
Project

DIANA - the analytical method for the determination of enzyme inhibition (GA19-10280S)

compounds with novel scaffolds will be verified using established enzyme kinetic assays. New inhibitors of these enzymes may open new avenues in primary research for identification of potent inhibitors of medicinally relev...

Biochemical research methods

  • 2019 - 2021
  • 5 295 tis. Kč
  • 4 944 tis. Kč
  • GA ČR
Project

Plasma activities of intracellular enzymes in selected inborn errors of metabolism - suitability for diagnosis and for predicting responsiveness to therapy. (NT14159)

of plasma activity of selected intracellular enzymes involved in metabolism of amino acids, purines and fatty acids and verify the basic hypothesis that the enzymes the methods of determining the plasma activity of these enzyme...

FG - Pediatrie

  • 2013 - 2015
  • 4 738 tis. Kč
  • 4 738 tis. Kč
  • MZ
Project

Functional Assays for Rapid Microbiological Diagnostics of Selected Health-Care Associated Infections (NV19-05-00541)

diagnostic microbiological assays is of utmost importance. Especially, functional diagnostics (i.e., detection of enzyme activity) is important in era of horizontal gene transfer. Functional assays for detection of selecte...

Microbiology

  • 2019 - 2022
  • 9 063 tis. Kč
  • 9 063 tis. Kč
  • MZ
Project

Role of BMH proteins in the regulation of yeast enzyme neutral trehalase (GAP207/11/0455)

–dependent regulation of the activity ofthe enzyme Neutral trehalase (NTH1). Site spectroscopy, X-raycrystallography, analytical ultracentrifugation and enzyme and is required in a variety stress conditions. Activity of theNTH1 ...

CE - Biochemie

  • 2011 - 2015
  • 5 975 tis. Kč
  • 5 975 tis. Kč
  • GA ČR
Project

Development of the enzyme immunoassay for the determination of organochlorine pesticides in foodstuffs (GA525/99/0271)

The aim of the project is to develop enzyme immunoassays (ELISAs) of DDT (dichlorodiphenyltrichloroethan) and endosulfan. The ELISAs will be developed on microplates, with both and their characterisation, 3) labelling of antibodies and/or ha...

CE - Biochemie

  • 1999 - 2001
  • 1 135 tis. Kč
  • 913 tis. Kč
  • GA ČR
Project

Capillary electrophoresis as a tool for the drug-metabolism studies (GA203/06/0047)

. Important group of detoxication enzymes - cytochromes P450 will be studied with respect to enzyme-drug interactions. The project will be focused on the development of capillary is filled with the buffer suitable for enzyme

CB - Analytická chemie, separace

  • 2006 - 2008
  • 1 797 tis. Kč
  • 1 389 tis. Kč
  • GA ČR
Project

Anti-inflammatory activity of plant quinones (GP525/09/P528)

of COX-2 and 5-LOX enzymes. Plant compounds are served as prospective source of these compounds. In vitro enzyme assay monitoring production of prostaglandins andleukotrienes) and lipoxygenases (LOXs) enzymes by p...

GM - Potravinářství

  • 2009 - 2011
  • 1 219 tis. Kč
  • 1 219 tis. Kč
  • GA ČR
Project

Application of capillary zone electrophoresis for the study of enzymes (GA203/03/1125)

The aim of the project is to improve and enlarge the applicability of CZE especially its modification EMMA (Electrophoretically Mediated MicroAnalysis) method for the assay and study of enzymes. EMMA utilizes differential electropho...

CE - Biochemie

  • 2003 - 2005
  • 1 491 tis. Kč
  • 966 tis. Kč
  • GA ČR
Project

Trypsin-like proteases from human parasite, blood fluke Schistosoma mansoni (ME10011)

Project will be focused on trypsin-like proteases from human blood fluke S. mansoni. Amino acid similarity of these enzymes to serine mammalian proteases which and biochemical properties of these enzymes. If hypothesis is validated,...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2010 - 2012
  • 2 400 tis. Kč
  • 2 400 tis. Kč
  • MŠMT
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