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17 667 (0,132s) •

Project

Structure-function relationship of protein (GP204/01/P055)

can be used to analyze structure-function relationships of indThe proposed method for the study of structure-function relations of proteins structure and function of proteins are of dive...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 325 tis. Kč
    • •
  • 325 tis. Kč
    • •
  • GA ČR
Project

Rational re-design of microbial enzymes involved in degradation of toxic organic pollutants. (ME 276)

-directed mutagenesis techniques. General structure-function relationshipsThe main objective of the project is the investigation of structure-function relationships of the enzymes involved in degr...

EB - Genetika a molekulární biologie

  • 1998 - 2002
    • •
  • 3 260 tis. Kč
    • •
  • 1 160 tis. Kč
    • •
  • MŠMT
Project

Lysosomal Proteinases and their Inhibitors - Structural and Functional Relationship (IAA455105)

CE - Biochemie

  • 1993 - 1995
    • •
  • 111 tis. Kč
    • •
  • 222 tis. Kč
    • •
  • AV ČR
Project

MAMMALIAN MICROSOMAL CYTOCHROME P450 INTERACTION WITH REDOX PARTNERS - TOPOLOGY AND STRUCTURE-FUNCTION RELATIONSHIPS (GAP207/12/0627)

The grant proposal is aimed to reveal the molecular structure, topology, organization and structure-function relationships of cytochrome P450 multienzyme complex, and also to understand the structure-f...

CE - Biochemie

  • 2012 - 2015
    • •
  • 7 574 tis. Kč
    • •
  • 7 574 tis. Kč
    • •
  • GA ČR
Project

Molecular mechanism of function of proteases in breast cancer (1P04OCB20.002)

The project is on structure-function relationship in cathepsin D protease playing a critical role in breast cancer....

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 2 400 tis. Kč
    • •
  • 1 800 tis. Kč
    • •
  • MŠMT
Project

Structure-functional Relationships of Haloalkane Dehalogenases (GAP207/12/0775)

of structure-function relationships of haloalkane dehalogenases and related a/b-hydrolases. compounds to corresponding alcohols. Until now, only four tertiary structures of these enzymes have been solved by X-ray ...

CD - Makromolekulární chemie

  • 2012 - 2016
    • •
  • 12 225 tis. Kč
    • •
  • 12 225 tis. Kč
    • •
  • GA ČR
Project

Structure-activity relationship (SAR) study of immunosuppressive effects of pyrimidine analogues (GAP303/12/0172)

of the extensive structure-activity relationship (SAR) study. The set of the compounds of the natural pyrimidine structure, all in combination with a number of specific substituents at the position C5. The immunosuppressiv...

FR - Farmakologie a lékárnická chemie

  • 2012 - 2016
    • •
  • 15 179 tis. Kč
    • •
  • 15 179 tis. Kč
    • •
  • GA ČR
Project

Relationship between structure of acetylcholinesterase reactivators and their reactivation potency (GP305/07/P162)

of relationship between structural factors and their influence on the reactivation potency is useful. Among them, presence and number of functional oxime groups, presence discussed.In this project, we would like to find ou...

FR - Farmakologie a lékárnická chemie

  • 2007 - 2009
    • •
  • 963 tis. Kč
    • •
  • 963 tis. Kč
    • •
  • GA ČR
Project

Biophysical study of MntH membrane transport proteins structure-function relationship (GA204/07/0558)

knowledge of the structure-function relationship in the MntH/Nramp family by studying the function of key residues in vivo, in vitro (right-side out vesicles, in-side out allows complementing the functional

BO - Biofyzika

  • 2007 - 2010
    • •
  • 1 979 tis. Kč
    • •
  • 1 979 tis. Kč
    • •
  • GA ČR
Project

Structure and function of proteins for biotechnologies and drug design (LG14009)

The project goal is to elucidate, in collaboration with the European infrastructure Instruct, principles of function of selected target enzymes and receptors based on structural studies, to design protein modifications for the purpo...

EB - Genetika a molekulární biologie

  • 2014 - 2016
    • •
  • 7 755 tis. Kč
    • •
  • 7 755 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 17 667