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14 (0,069s)

Project

Prevalence of spasticity in patients suffering from ischaemic stroke in the internal carotid artery territory (NV15-31921A)

Observational, analytic, prospective, longitudinal, cohort study to assess the prevalence of spasticity in patients suffering from first-ever stroke in the internal carotid artery territory. Patients will be recruited according to the inclus...

FH - Neurologie, neurochirurgie, neurovědy

  • 2015 - 2018
  • 3 993 tis. Kč
  • 3 579 tis. Kč
  • MZ
Project

Changes of motor and premotor cortex organization and activation following botulinum toxin injection in ischemic stroke patients suffering from spasticity an fMRI study (NS9920)

Project studies the central correlate of spasticity after stroke and its changes after botulinum toxin injection by comparing motor tests, neurophysiology and maps of premotor and motor cortices from functional magnetic resonance imaging.......

FH - Neurologie, neurochirurgie, neurovědy

  • 2008 - 2011
  • 2 497 tis. Kč
  • 2 419 tis. Kč
  • MZ
Project

Long-term intrathecal administration of baclofen for severe spasticity in multiple sclerosis patients (NR8523)

To create scheme for selection of patients with chronic progressive form of multiple sclerosis suitable for pump implantation with continual intrathecal baclofen and resolve the problem of insufficient treatment of severe spasticity in these...

FH - Neurologie, neurochirurgie, neurovědy

  • 2005 - 2007
  • 914 tis. Kč
  • 833 tis. Kč
  • MZ
Project

Video-assisted tenotomies of tendons of shortened muscles in spastic form of cerebral palsy (ND7585)

Introduction of mini-invasive method of video-assisted tenotomies of tendons of shortened muscles in cerebral palsy patients...

FH - Neurologie, neurochirurgie, neurovědy

  • 2003 - 2005
  • 1 347 tis. Kč
  • 1 142 tis. Kč
  • MZ
Project

Gene therapy of neuropathic pain and spasticity via subpial application of AAV vectors in area of spinal cord roots of sciatic nerve and spinal cord injury in minipigs (LTAUSA19029)

spasticity is hampered by the absence of suitable large animal preclinical models. Due and spasticity models). A cornerstone for cooperation is recently developed subpial in ameliorating symptoms of neuropathic pain and muscle

Neurosciences (including psychophysiology)

  • 2020 - 2023
  • 11 385 tis. Kč
  • 11 385 tis. Kč
  • MŠMT
Project

Selective posterior rhizotomy for spasticity in children with cerebral palsy (ND6305)

Selective posterior rhizotomy is an effective method in treatment of spasticity in children with cerebral palsy. With intraoperative monitoring dorsal roots of L1 to S2 are subdivided at three to six rootlets. Selected rootlets are than cut ...

FJ - Chirurgie včetně transplantologie

  • 2000 - 2002
  • 3 030 tis. Kč
  • 3 030 tis. Kč
  • MZ
Project

Viscoelasticity of soft tissue and its identification in vivo, in situ (GP106/09/P326)

(reologic) properties of spastic muscle. Clinical medicine such as neurology and rehabilitation encounter patients suffering from spasticity, which medicine attempts properties of the afflicted spastic muscle must first be...

EI - Biotechnologie a bionika

  • 2009 - 2011
  • 695 tis. Kč
  • 695 tis. Kč
  • GA ČR
Project

Changes in cortical organization and activation in patients with post-stroke spasticity following botulinum toxin treatment fMRI study (NT13575)

For proposed project we will use methodology and obtained detailed knowledges about changes in motor, premotor and other non-motor representation of hand movement following from botulinum toxin treatment of spasticity. Our earlier suppositio...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
  • 5 599 tis. Kč
  • 5 599 tis. Kč
  • MZ
Project

Sensorimotor network modulation by targeted therapy of post-stroke spasticity (NV17-29452A)

Post-stroke spasticity (PSS) is one of the major sequelae following ischemic stroke. Ischemic lesions of descending motor tracts result in upper motor neuron syndrome comprising both negative signs (weakness and loss of dexterity) and positi...

FH - Neurologie, neurochirurgie, neurovědy

  • 2017 - 2021
  • 8 275 tis. Kč
  • 8 233 tis. Kč
  • MZ
Project

Suprasegmental effects of selective posterior rhizotomy (NR8318)

The aim of the study is to evaluate the suprasegmental effects of selective posterior rhizotomy. Electrophysiologic measurements will be carried out before and after the surgery. Changes in fonation, eye movements, upper extremities reflexes and cort...

FH - Neurologie, neurochirurgie, neurovědy

  • 2005 - 2007
  • 2 239 tis. Kč
  • 2 125 tis. Kč
  • MZ
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