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1 102 (0,1s) •

Project

The development of lower urinary tract dysfunction in remittent form of multiple sclerosis on dependency of neurological treatment. (NR8188)

The prospective study of development of lower urinary tract dysfunction in patients treated by drugs of the first choice for remittent stadium of multiple sclerosis (interferons) and the patients treated by combine immunosuppressive...

FH - Neurologie, neurochirurgie, neurovědy

  • 2004 - 2006
    • •
  • 1 999 tis. Kč
    • •
  • 1 569 tis. Kč
    • •
  • MZ
Project

Cytokines in relationship to immunoglobulin production in multiple sclerosis. (IZ2777)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1995 - 1997
    • •
  • 1 155 tis. Kč
    • •
  • 1 155 tis. Kč
    • •
  • MZ
Project

Osteoporosis in multiple sclerosis patients the impact of corticosteroids and immobility on its development, possibilities and therapy (NF6780)

Osteodensitometric and laboratory examinations of multiple sclerosis patientsfollowed in MS Center will be carried out to determine the exte of osteopenia and osteoporosis to establish the impact of steroid therapy on increased bone...

FH - Neurologie, neurochirurgie, neurovědy

  • 2001 - 2003
    • •
  • 2 748 tis. Kč
    • •
  • 2 712 tis. Kč
    • •
  • MZ
Project

Long-term intrathecal administration of baclofen for severe spasticity in multiple sclerosis patients (NR8523)

To create scheme for selection of patients with chronic progressive form of multiple sclerosis suitable for pump implantation with continual intrathecal baclofen and resolve the problem of insufficient treatment of severe spasticity...

FH - Neurologie, neurochirurgie, neurovědy

  • 2005 - 2007
    • •
  • 914 tis. Kč
    • •
  • 833 tis. Kč
    • •
  • MZ
Project

Pharmacogenomics - a promising way for reasonable and efficacious multiple sclerosis treatment (1A8713)

Observation of seleted genes expression in patients with the first attack of neurological symptomatology suspected of multiple sclerosis development before and after the initiation of interferon beta treatment. Efficacy of interfero...

EB - Genetika a molekulární biologie

  • 2005 - 2010
    • •
  • 7 909 tis. Kč
    • •
  • 7 789 tis. Kč
    • •
  • MZ
Project

The use of plasticity of the central nervous system in neurorehabilitation of multiple sclerosis people (1A8628)

The aim of this study is to prove that neuro-rehabilitation in multiple sclerosis causes the adaptation and reorganization of the central nervous system function on the system basis, which is supposed to result in brain activity cha...

FH - Neurologie, neurochirurgie, neurovědy

  • 2005 - 2009
    • •
  • 3 134 tis. Kč
    • •
  • 2 668 tis. Kč
    • •
  • MZ
Project

Detection of antibodies generated as a reaction on demaged neural tissue (NR8114)

We want to measure autoantibodies directed to protein beta-tubulin class III, generated by specific immunity as a marker of the axonal loss together with the progression of Multiple Sclerosis in cooperation with MS center 2nd medica...

FH - Neurologie, neurochirurgie, neurovědy

  • 2004 - 2006
    • •
  • 2 586 tis. Kč
    • •
  • 2 552 tis. Kč
    • •
  • MZ
Project

Specific characteristics of neuropathic pain of central and peripheral type (NT13523)

and patients with multiple sclerosis without any pain. The obtained results with multiple sclerosis and chronic low back pain will be assessed. of various types of neuropathic pain, in particular central neuropath...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
    • •
  • 5 723 tis. Kč
    • •
  • 5 723 tis. Kč
    • •
  • MZ
Project

The role of neurosteroids in the etiopathogenesis of multiple sclerosis (NT13814)

In serum and cerebrospinal fluid of 60 patients with MS (40 women in the both phases of the menstrual cycle and 20 men) the steroid metabolom will be investigated. Levels of steroid hormones in serum and cerebrospinal fluid will be monitored as well ...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2012 - 2015
    • •
  • 4 302 tis. Kč
    • •
  • 4 302 tis. Kč
    • •
  • MZ
Project

Immunoablative therapy with haematopoietic stem cell support in the management of the intractable form of multiple sclerosis. (NF6560)

Phase II clinical study of immunoablative treatment with autologous T-cell depleted progenitor cell support in advanced, conventional treatment unresponsive multiple sclerosis. Primary goal of the study is to explore the effect of h...

FE - Ostatní obory vnitřního lékařství

  • 2001 - 2003
    • •
  • 7 873 tis. Kč
    • •
  • 7 810 tis. Kč
    • •
  • MZ
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