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597 (0,085s) •

Project

Mechanism of the melatonin effect on second and third messengers in neonatal rat gonadotrophs (IAA5011705)

bound receptors to inhibit GnRH-induced Lh release. The mechanism of the effect involves inhibition of GnRH-induced (Ca2+)i increase. Melatonin blocks Ca2 inhibition of Ca2+ influx through voltage-sensitive channels may in...

ED - Fyziologie

  • 1997 - 2000
    • •
  • 2 595 tis. Kč
    • •
  • 1 353 tis. Kč
    • •
  • AV ČR
Project

Species specific growth inhibition in Salmonella spp. (ME 077)

The project is focused on genus specific growth inhibition among Salmonella strains in vitro. Understanding of the phenomenon can be utilised in the precolonization of hatching chickens with atenuated vaccine. It was demonstrated and molecul...

EE - Mikrobiologie, virologie

  • 1997 - 1999
    • •
  • 1 450 tis. Kč
    • •
  • 810 tis. Kč
    • •
  • MŠMT
Project

*Ecologically friendly inhibition of pathogenic bacteria and algae proliferation in the circulation cooling systems of nuclear power stations and the other similar technological installations. (FT-TA/034)

*Development of the new, ecologically friendly method of algae and bacteria proliferation inhibition due to singlet oxygen, generated in the cooling circuits of nuclear power stations at Temalín and Dukovany and in the other industrial cooli...

CC - Organická chemie

  • 2004 - 2006
    • •
  • 11 373 tis. Kč
    • •
  • 9 575 tis. Kč
    • •
  • MPO
Project

Mechanism of the inhibitory effect of melatonin on GnRH-induced (Ca2+), increase and LH release in neonatal rat gonadotrophs (GA309/97/0513)

previous project we have found that malatonin inhibits GnRH-induced(Ca2+) increase mobilization of calcium. The melatonin inhibition of Ca2+ influx through voltage-sensitive increase of Na+ and melatonin blocks the effect. Melatoni...

ED - Fyziologie

  • 1997 - 1999
    • •
  • 3 938 tis. Kč
    • •
  • 2 989 tis. Kč
    • •
  • GA ČR
Project

Inhibition of FOXO3-DNA interaction by small molecule inhibitors (GF17-33854L)

in certain cancer types. To date no compounds that directly bind and inhibit the activity with the DNA-binding domain of FOXO3 and efficiently inhibit its transcriptional activity inhibition of target recognition by FOXO3 ...

CE - Biochemie

  • 2017 - 2019
    • •
  • 7 063 tis. Kč
    • •
  • 6 675 tis. Kč
    • •
  • GA ČR
Project

New wound dressings with programmed release of active substances for biofilm inhibition. (TA03011029)

inhibition of wound pathogens biofilm, that is gentle for patients. The project will be based on the principle of biofilm inhibition by programmed release of iodine using the benefit of inhibition of bacterial quorum sensi...

FO - Dermatovenerologie

  • 2013 - 2015
    • •
  • 9 890 tis. Kč
    • •
  • 6 400 tis. Kč
    • •
  • TA ČR
Project

Possibilities of inhibition process of coal oxidation (GA105/00/1416)

and quantify physical and chemical types of interaction between coal and and inhibiting treatnent of coal by inhibiting agents.Possible mechanistic pathways of inhibitors......

DH - Báňský průmysl včetně těžby a zpracování uhlí

  • 2000 - 2002
    • •
  • 1 732 tis. Kč
    • •
  • 1 132 tis. Kč
    • •
  • GA ČR
Project

Study of the activation and inhibition of retroviral proteases (IAA4055503)

CE - Biochemie

  • 1995 - 1997
    • •
  • 730 tis. Kč
    • •
  • 730 tis. Kč
    • •
  • AV ČR
Project

Initiation and Inhibition of Freezing of Plants by Endogenous Factors (GA501/93/0328)

9B - 9

  • 1993 - 1995
    • •
  • 204 tis. Kč
    • •
  • 408 tis. Kč
    • •
  • GA ČR
Project

Using the experimental and theoretical methods for structure analysis of HIV protease complexes with selected inhibitors (IAA4050811)

of the inhibition differences observed with wild and mutated protease and to generalize of the present medicaments used against AIDS based on HIV protease inhibition is an ability not inhibited by the drug used. Structure ...

CD - Makromolekulární chemie

  • 1998 - 2001
    • •
  • 7 855 tis. Kč
    • •
  • 3 428 tis. Kč
    • •
  • AV ČR
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