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37 (0,076s) •

Project

Study of genetic determination of resistance and dyslipidemia in model inbred rat strain PD/Cub (GA303/01/1010)

Coronary heart disease, hypertension, non-insulin-dependent diabetes and obesity are major causes of ill health in industrial societies. Disturbances of carbohydrate and lipid metabolism, such as insulin resistance and dyslipidemia, are a co...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2001 - 2003
    • •
  • 2 785 tis. Kč
    • •
  • 2 785 tis. Kč
    • •
  • GA ČR
Project

Effects of environmental factors, gene predisposition and psychological impact of genetic testing on efficacy of lipid lowering treatment (NS10579)

Evaluation of the impact of genetic determination of dyslipidemia on therapeutic efficacy of statin treatment by assessment of gene polymorphisms. Assessment of impact of genetic testing awareness on efficacy of statin treatment.......

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2009 - 2011
    • •
  • 4 883 tis. Kč
    • •
  • 4 883 tis. Kč
    • •
  • MZ
Project

Genetic and factors of life style by children with metabolic syndrom and their dependents. Diagnostic and interference. (NS10589)

The observance of signification of laboratory, antropometric and genetic determination for the presence s obesity, dyslipidemia and metabolic syndrome and response to dietary and regime interventions in children, selection of risk patients a...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2009 - 2011
    • •
  • 4 815 tis. Kč
    • •
  • 4 815 tis. Kč
    • •
  • MZ
Project

Interaction of diatery factors with some single genetic polymorphisms in pathogenesis of atherogenic dyslipidemias with hyperapolipoproteinemia B-100 (NR8149)

Group of 240 patients with aterogenic dyslipidemia (with hyper apoB100)will be examined for plasma lipids, lipoproteins, single nucleotide polymorphisms of MTP, FABP-2, PPAR-gamma-2, dietary composition, cholesterol absorption and synthesis....

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2006
    • •
  • 2 941 tis. Kč
    • •
  • 2 433 tis. Kč
    • •
  • MZ
Project

Prevalence and incidence of major CVD risk factors, longitudinal trend analysis in a population random sample of the Czech Republic, Czech post-MONICA study (NR9389)

Major CVD risk factors in a 1% random sample of the general population of the Czech Republic will be monitored on a longitudinal basis. The prevalence of chronic kidney disease will be determined in a population random sample. The incidence of hypert...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2007 - 2009
    • •
  • 14 049 tis. Kč
    • •
  • 11 462 tis. Kč
    • •
  • MZ
Project

Dyslipidemia and prehypertension - association of dyslipidemic phenotypes with prevalence of prehypertension. Association of prehypertension with markers of insulin resistance, inflammation (NS10284)

I. Association of individual dyslipidemic phenotypes with prevalence of prehypertension and hypertension. II. Association of blood pressure and other risk factors of atherosclerosis, particularly with lipid parameters, markers of insulin resistance, ...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2009 - 2011
    • •
  • 3 334 tis. Kč
    • •
  • 3 314 tis. Kč
    • •
  • MZ
Project

Dyslipidemia classification based on concentration of apolipoprotein B and triglycerides. Association of dyslipidemic phenotypes with indices of insulin resistance, inflammation and thrombosis (NR9068)

Classification of dyslipidemias on the basis of apolipoprotein B and triglyceride concentrations. Association of dyslipidemic phenotypes with markers of insulin resitance and adiponectin concentrations. Association of dyslipidemic phenotypes...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2006 - 2008
    • •
  • 3 029 tis. Kč
    • •
  • 3 029 tis. Kč
    • •
  • MZ
Project

Molecular mapping and positional cloning of genes that are responsible for clustering of cardiovascular risk factors (GA305/00/1646)

Insulin resistance and dyslipidemia have been frequently observed in patients with essential hypertension and in spontaneously hypertensive rats (SHR). Our recent results showed that genes responsible for this clustering of clustering of car...

EB - Genetika a molekulární biologie

  • 2000 - 2002
    • •
  • 2 919 tis. Kč
    • •
  • 2 505 tis. Kč
    • •
  • GA ČR
Project

Genetic and factors of life style by children with markers of the metabolic syndrom and their dependents. Diagnostic and interference. -II (NT14152)

The observance of signification of laboratory, antropometric and genetic determination for the presence s obesity, dyslipidemia and metabolic syndrome and response to dietary and regime interventions in children, selection of risk patients a...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2013 - 2015
    • •
  • 5 381 tis. Kč
    • •
  • 5 381 tis. Kč
    • •
  • MZ
Project

Genetic aspects of the metabolic programming in rat models of dyslipidemia and insulin resistance (KJB5105401)

The endocrine programming of several metabolic parameters is now firmly established. However, the responsible mechanisms are far from being fully understood. We have recently established several rad models of dislipidemia and insulin resistance. In t...

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 1 348 tis. Kč
    • •
  • 1 348 tis. Kč
    • •
  • AV ČR
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