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Role of AMP-activated protein kinase in the modulation of lipid metabolism in white adipose tissue (KJB5011303)
in adipocytes is affected by the energy status of these cells and that the energy statusis adiposity). A similar situation occurs when synthesis of ATP in adipocytes is lowered of adipocytes affects lipid metabolism via AM...
EB - Genetika a molekulární biologie
- 2003 - 2005 •
- 1 823 tis. Kč •
- 1 049 tis. Kč •
- AV ČR
Řešení projektu: 1. 1. 2003 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (58%)
Poskytovatel: Akademie věd České republiky
Polychlorinated persistent organic pollutants in the etiopathogenesis of obesity and insulin resistance (NT14330)
The aim of study is in experiment in vitro, on cell lines of adipocytes (multipotent adipose-derived stem cells, preadipocytes adipocytes) to observe effects adipocytes to measure expression of genes involved in insulin sig...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2013 - 2015 •
- 4 325 tis. Kč •
- 4 325 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2013 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Plasticity of white adipose tissue in mice physiological relevance and implication for obesity-resistance (GA16-05151S)
. changes in size and number of adipocytes. Both, (i) combined treatment using calorie adipocytes, and (ii) recruitment of new adipocytes exhibiting a high capacity for FFA removal. Enhanced lipid metabolism in adipocyt...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2016 - 2018 •
- 8 070 tis. Kč •
- 7 297 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2016 - 31. 12. 2018
Uznané náklady
Podpora ze státního rozpočtu (90%)
Poskytovatel: Grantová agentura České republiky
Reduced accumulation of fat due to omega-3 polyunsaturated fatty acid and leptin involvement of mitochondrial and lipid metabolism in adipocytes (GA303/02/1220)
have functions in adipocytes. Our previous studies on transgenic mice indicated that uncoupling of mitochondrial oxidative phosphorylation in adipocytes could be a biological fatty acid synthesis in adipocytes. Experiments...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2002 - 2004 •
- 4 640 tis. Kč •
- 2 939 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2002 - 1. 1. 2004
Uznané náklady
Podpora ze státního rozpočtu (63%)
Poskytovatel: Grantová agentura České republiky
Metabolism of eicosanoids in adipose tissue molecular mechanisms with respect to fatty acid substrate (GP13-04449P)
Obesity is associated with a low-grade inflammation of adipose tissue when pro-inflammatory macrophages negatively affect adipocytes. We have shown that n-3 long chain mice, but the molecular mechanisms and contribution of either adipocy...
EB - Genetika a molekulární biologie
- 2013 - 2015 •
- 3 287 tis. Kč •
- 3 207 tis. Kč •
- GA ČR
Řešení projektu: 1. 2. 2013 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (98%)
Poskytovatel: Grantová agentura České republiky
Physiological significance of the long and short variants of Gs-a protein (GA305/00/1660)
of brown adipocytes and heart failure. Our preliminary observations indicated that differentiation of cultured brown adipocytes is accompanied by distinct changes in both of these interventions on the differentiation process of bro...
ED - Fyziologie
- 2000 - 2002 •
- 4 405 tis. Kč •
- 2 672 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2000 - 1. 1. 2002
Uznané náklady
Podpora ze státního rozpočtu (61%)
Poskytovatel: Grantová agentura České republiky
Impact of emerging chlorinated contaminants on adipogeneses (GA21-19437S)
syndrome and affect differentiation of adipocytes. However, with regards to differing of Czech population. Investigation of CPs influence on adipocyte differentiation......
Occupational health
- 2021 - 2023 •
- 6 690 tis. Kč •
- 5 940 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2021 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (89%)
Poskytovatel: Grantová agentura České republiky
New mechanism for the control of gene expression by fatty acids in adipocytes (KJB5011410)
that gene expression in adipocytes was affected by cellular energy charge (reflected...
EB - Genetika a molekulární biologie
- 2004 - 2006 •
- 1 239 tis. Kč •
- 999 tis. Kč •
- AV ČR
Řešení projektu: 1. 1. 2004 - 1. 1. 2006
Uznané náklady
Podpora ze státního rozpočtu (81%)
Poskytovatel: Akademie věd České republiky
The role of endoplasmic reticulum stress in the pathogenesis of obesity-related inflammation in human adipose tissue (GAP301/11/0748)
Efficient treatment of obesity and metabolic syndrome will be based on understanding of adipose tissue (AT) role in the pathogenesis of insulin resistance and proinflammatory state. Adipocytes of obese produce proinflammatory cytokines and s...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2011 - 2014 •
- 6 444 tis. Kč •
- 6 444 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2011 - 31. 12. 2014
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
DIABAT - Recruitment and activation of brown adipocytes as preventive and curative therapy for type 2 diabetes (7E12073)
The DIABAT project will employ knowledge of the function, dysfunction and physiological regulation of brown adipocytes to develop innovative therapeutic and preventive strategies for type 2 diabetes. Brown adipose tissue (BAT) is currently a...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2012 - 2015 •
- 3 270 tis. Kč •
- 3 270 tis. Kč •
- MŠMT
Řešení projektu: 1. 1. 2012 - 30. 9. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
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