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747 (0,129s) •

Project

New paradigm for functional contrast agent for 31P magnetic resonance imaging (NU20-08-00095)

phosphorus-containing contrast agents for 1H/31P magnetic resonance (MR). The main by biodegradable linkers to Gd3+ or Fe3+, is their ability to switch between 1H and 31P MR as T1 contrast agents for ...

Biophysics

  • 2020 - 2023
    • •
  • 12 608 tis. Kč
    • •
  • 12 608 tis. Kč
    • •
  • MZ
Project

Paramagnetic switches in polymer contrast agents for 19F and 31P magnetic resonance The new paradigm in noninvasive cancer functional imaging (LTC19032)

The aim of this project is to develop a conceptually new class of cancer-aimed biodegradable phosphorus or fluorine-containing polymer contrast agents for 1H / 31P or 1H / 19F magnetic resonance (MR) providing bot...

Polymer science

  • 2019 - 2022
    • •
  • 4 920 tis. Kč
    • •
  • 4 920 tis. Kč
    • •
  • MŠMT
Project

SPRES-new methods for localized single-voxel in vivo 1H and 31P NMR spectroscopy. (IAA4065601)

The theme of the project consists in a quality assessment and further improvements of new sequences for the localized single voxel in vivo 1H and 31P magnetic resonance spectroscopy (MRS) and for spectrally and spatially ta...

CE - Biochemie

  • 1996 - 1998
    • •
  • 1 830 tis. Kč
    • •
  • 640 tis. Kč
    • •
  • AV ČR
Project

NMR Toolbox for Probing Stereochemistry in Phosphorus-Containing Bioactive Molecules (GA21-23014S)

idea of the project lies in using 31P as a magnetically active isotope providing the key interactions with 13C and 1H nuclei. Implementing 31P-13C and 31P-1H couplings, develop the P-based NMR experiments...

Analytical chemistry

  • 2021 - 2023
    • •
  • 5 851 tis. Kč
    • •
  • 5 688 tis. Kč
    • •
  • GA ČR
Project

Advanced excitation and detection systems for magnetic resonance imaging and localised spectroscopy (GA102/00/1262)

The topic of the proposed project is the research and design of new types of resonators for 1H MR (magnetic resonance) tomography and 1H and 31P localized MR spectroscopy of the human head (250 mm in diame...

JA - Elektronika a optoelektronika, elektrotechnika

  • 2000 - 2002
    • •
  • 5 595 tis. Kč
    • •
  • 1 609 tis. Kč
    • •
  • GA ČR
Project

Study of the viability and physiological changes in human renal allografts using magnetic resonance (GA308/96/0837)

The aim of the project is to the possibility of reliable determination of the viability of human cadaverous kidneys intended for transplantation by 1H MR relaxometry and to develop a standard method for organ guality assessment. Part of the ...

EA - Morfologické obory a cytologie

  • 1996 - 1998
    • •
  • 1 223 tis. Kč
    • •
  • 1 223 tis. Kč
    • •
  • GA ČR
Project

Noninvasive hepatitis C virus detection in liver and brain by 31 MR spectroscopy (NR7853)

The project objective is the correlation between clinical and MR data of the liver and brain in patients with hepatitis C and thus make a contribution to clinical evaluation of those patients and to an appropriate treatment plan proposal. 1H...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2004 - 2006
    • •
  • 2 386 tis. Kč
    • •
  • 2 221 tis. Kč
    • •
  • MZ
Project

Reliable calculations and predictions of NMR chemical shifts for the structural characterization of phosphorylated intrinsically disordered proteins (GJ19-14886Y)

magnetic resonance (NMR) chemical shifts (CSs) in phosphorylated intrinsically computations combining molecular dynamics and quantum-chemical calculations to obtain 1H, 13C, 15N and 31P chemical shifts. In addition, we wil...

Physical chemistry

  • 2019 - 2022
    • •
  • 5 250 tis. Kč
    • •
  • 5 250 tis. Kč
    • •
  • GA ČR
Project

Monitoring of hepatic fat metabolism using Magnetic Resonance methods (NV16-28427A)

or removed triglycerides in the liver. Our study is based on 1H MR single voxel...

FP - Ostatní lékařské obory

  • 2016 - 2020
    • •
  • 7 034 tis. Kč
    • •
  • 6 999 tis. Kč
    • •
  • MZ
Project

Proton Magnetic Resonance Spectroscopy Correlation with Neuropathological Findings in Patients with Mesial Temporal Lobe Epilepsy (GP309/02/D076)

Proton magnetic resonance spectroscopy (1H MRS) is a new diagnostic technique. A major contribution of 1H MRS to evaluation of patients with mesial temporal in frequently occurring bilateral 1H MRS abnormalities in...

FH - Neurologie, neurochirurgie, neurovědy

  • 2002 - 2005
    • •
  • 846 tis. Kč
    • •
  • 846 tis. Kč
    • •
  • GA ČR
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