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866 (0,124s) •

Project

Could better diagnostics and therapy of hypertension improve post-renal transplantation graft survival and cardiovascular risk profile in children (NE7629)

transplantation that impairs graft as well as patient survival. Patients with controlled hypertension have similar graft survival to patients with normal blood pressure contribute to worse long-term graft...

FG - Pediatrie

  • 2003 - 2005
    • •
  • 930 tis. Kč
    • •
  • 924 tis. Kč
    • •
  • MZ
Project

Use kidney grafts from very young children to transplantation for adult recipients (IZ3972)

Procurement of high number kidney grafts from very young children to transplantation for adult recipients. Continual observation short term and long term survival kidney grafts.......

FJ - Chirurgie včetně transplantologie

  • 1997 - 1999
    • •
  • 6 192 tis. Kč
    • •
  • 5 575 tis. Kč
    • •
  • MZ
Project

Treatment of proteinuria and hypertension with angiotensin-converting enzyme inhibitor in children after renal transplantation (NR9524)

Proteinuria together with arterial hypertension is a common complication in children after renal transplantation. It reduces survival of the renal graft as well as survival of transplanted patients. Angiotensin-converting e...

FG - Pediatrie

  • 2007 - 2009
    • •
  • 2 456 tis. Kč
    • •
  • 2 322 tis. Kč
    • •
  • MZ
Project

The incidence of subclinical rejection in protocol biopsies of renal transplants, the possibilities of its diagnostics and influence on long-term renal graft survival. (NK7741)

In addition to HLA-nondependent factors, HLA-dependent factors play an important role in the development of chronic transplant enphropathy. The objective of the study is to evaluate the incidence of subclinical rejection in protocol biopsies and its ...

FJ - Chirurgie včetně transplantologie

  • 2003 - 2005
    • •
  • 1 211 tis. Kč
    • •
  • 1 156 tis. Kč
    • •
  • MZ
Project

Transplantation of the embryonic cerebellar tissue and stem cells into the cerebellum of Lurcher mutant and normal mice (OC10038)

of the graft. We will compare survival and possible functional effect of individual typesThe aim of the project is to investigate long-term survival of embryonic cerebellar tissue in the form of a solid graft or c...

FH - Neurologie, neurochirurgie, neurovědy

  • 2010 - 2011
    • •
  • 793 tis. Kč
    • •
  • 793 tis. Kč
    • •
  • MŠMT
Project

Modulace regenerace poraněné míchy prostřednictvím neurálních progenitorů (MEB0808108)

of grafts survival, incorporation and diferenciation in host tissue. To analyze the connections between surviving graft and his potencial affection, that should display - intraspinal grafting, multiple mi...

FH - Neurologie, neurochirurgie, neurovědy

  • 2008 - 2009
    • •
  • 129 tis. Kč
    • •
  • 76 tis. Kč
    • •
  • MŠMT
Project

System for Continuous Early Postoperative Monitoring of Kidney Graft Blood Perfusion (NV16-34134A)

. They often lead to graft failure, if not intervened immediately. Nowadays, we lack diagnostic means, to monitor graft perfusion continuously. In the project, we would like to develop and test a kidney graft monitoring sys...

FJ - Chirurgie včetně transplantologie

  • 2016 - 2020
    • •
  • 7 425 tis. Kč
    • •
  • 7 276 tis. Kč
    • •
  • MZ
Project

Markers of transplantation tolerance after renal transplantation (NS10517)

rejection episodes and, finally, with graft survival over the first year post-transplantUnder this project, 75 renal graft recipients at risk of developing rejection FoxP3, TOAG and alpha2 mannosidase genes in peripheral b...

EB - Genetika a molekulární biologie

  • 2009 - 2011
    • •
  • 4 797 tis. Kč
    • •
  • 4 797 tis. Kč
    • •
  • MZ
Project

Vascular rejection phenotype after kidney transplantation and isolated v-lesion (NV15-26519A)

and consequent surveillance biopsies. Furthermore, impact of the AVR phenotypes on graft function and graft survival, response to immunosuppressive therapy will be assessed. impact on kidney allograft survival. A...

FJ - Chirurgie včetně transplantologie

  • 2015 - 2018
    • •
  • 6 458 tis. Kč
    • •
  • 6 458 tis. Kč
    • •
  • MZ
Project

Development of OPN-305 as an orphan drug for the treatment of Delayed Graft Function post solid organ transplantation (7E12023)

dialysis and hospitalisation, and increases the likelihood of graft failure and ultimately the duration of renal graft survival-expectancy. The incidence of DGF occurs in 21-44% of cases following cadaveric renal graft...

FJ - Chirurgie včetně transplantologie

  • 2012 - 2013
    • •
  • 2 786 tis. Kč
    • •
  • 2 786 tis. Kč
    • •
  • MŠMT
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