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7 (0,146s) •

Project

Red blood cell sodium and potassium transport in subjects with insulin resistance - effects of acute hyperinsulanaemia, hyperglycaemia and serum lipids (NB6682)

The aim of the study is to assess the erythrocyte ion transport in insulin-resistant subjects and to test the effect of acute in vivo induced hyperinsulinaemia, acute hyperglycaemia and 3-week treatment with fluvastatine.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2001 - 2003
    • •
  • 4 771 tis. Kč
    • •
  • 4 490 tis. Kč
    • •
  • MZ
Project

The effect of acute hyperinsulinaemia and hyperglycaemia on susceptibility to oxidation and fatty acid pattern of low density lipoproteinn in NIDDM patients (IZ3550)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1996 - 1998
    • •
  • 917 tis. Kč
    • •
  • 917 tis. Kč
    • •
  • MZ
Project

Validation of diagnostic approach in children and adolescents with randomly found hyperglycemia. (NB7420)

In about 100 children and adolescents, the cause of randomly found hyperglycemia will be estimated using metabolic investigation, estimation of autoantibodies and molecular genetic analysis. A diagnostic flowchart for clinical routine will be develop...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
    • •
  • 2 341 tis. Kč
    • •
  • 2 322 tis. Kč
    • •
  • MZ
Project

The role of cytokines, prostanoids and other vasoactive systems in the regulation of renal haemodynamics and renal sodium handling in IDDM patients. (IZ4242)

The aim of the study is to measure some vasoactive humoral system activities in relation to renal haemodynamics and renal sodium handling in IDDM patients without nephropathy, IDDM patients with microalbuminuria and healthy controls. Evaluate the eff...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1997 - 1999
    • •
  • 2 066 tis. Kč
    • •
  • 1 809 tis. Kč
    • •
  • MZ
Project

Immunologic parameters in patients with diabetic foot, their association with diabetes control and potential for their modulation. (NB5323)

The object of the Project is assessment of 1. immunologic of parameters in patients with diabetic foot 2. the relations between immunologic parameters and diabetes control and acute hyperglycaemia 3. the possibility of modulation of immunol....

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1999 - 2001
    • •
  • 1 479 tis. Kč
    • •
  • 1 479 tis. Kč
    • •
  • MZ
Project

Functional analysis of the RAGE gene susceptibility haplotype and its role in the hyperglycemia-driven pathology (KJB501620601)

Formation of Advanced Glycation End-products (AGEs) and subsequent activation of the Receptor of AGEs (RAGE) represents one of the principal pathogenic mechanisms of hyperglycaemia-induced cell damage. AGE/RAGE interaction activates several ...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2006 - 2008
    • •
  • 563 tis. Kč
    • •
  • 563 tis. Kč
    • •
  • AV ČR
Project

Proteomic and genetic assessment of sperm quality for the enhancement of assisted reproduction in infertile patients with diabetes mellitus (NV15-30880A)

The increasing frequency of infertility has become a major public health concern. Male infertility is the primary or contributing cause in approximately 60% of all cases. Diabetes mellitus (DM) reflected by persistent hyperglycaemia (PH) is ...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2015 - 2018
    • •
  • 10 948 tis. Kč
    • •
  • 10 948 tis. Kč
    • •
  • MZ
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