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6 (0,085s) •

Project

Molecular biology basis of adenylosuccinate lyase deficiency. (IZ3608)

FG - Pediatrie

  • 1996 - 1998
    • •
  • 2 450 tis. Kč
    • •
  • 2 450 tis. Kč
    • •
  • MZ
Project

Long-term monitoring of complex cardiovascular profile in the mother, fetus and offspring descending from pregnancy related complications (NV16-27761A)

Pregnancy represents a physiological stressor that may contribute to the inducement of severe chronic diseases later in the life. The risk of latter development of chronic diseases increases in women with pregnancy related complications (preeclampsia...

EB - Genetika a molekulární biologie

  • 2016 - 2019
    • •
  • 10 389 tis. Kč
    • •
  • 10 389 tis. Kč
    • •
  • MZ
Project

Analysis of genetic variants associated with intellectual disability and autism spectrum disorders using next generation sequencing (NV17-29423A)

From the genetics perspective intellectual disability and autism spectrum disorders are a large heterogeneous group of rare diseases. Exomes will be sequenced in about 100 families with sporadic or familial occurrence of affected children. Variants w...

EB - Genetika a molekulární biologie

  • 2017 - 2020
    • •
  • 11 653 tis. Kč
    • •
  • 11 653 tis. Kč
    • •
  • MZ
Project

Studies of aetiopathogenesis and optimising management in children with intrauterine growth restriction and persistent postnatal growth failure (NV18-07-00283)

About 5% of all neonates are born small-for-gestational-age (SGA) due to intrauterine growth restriction (IUGR) - with birth weight and/or length below -2 SD. About 90% of them experience spontaneous catch-up growth within the first two years of life...

Endocrinology and metabolism (including diabetes, hormones)

  • 2018 - 2022
    • •
  • 11 406 tis. Kč
    • •
  • 11 406 tis. Kč
    • •
  • MZ
Project

Exploring the Therapeutic Potential of Ketamine Enantiomers to Address Attentional and Cognitive Impairments in GRIN-related Disorder Model (NW24J-04-00084)

GRIN-related disorders are a group of neurodevelopmental disorders resulting from mutations in genes responsible for encoding N-methyl-D-aspartate receptor (NMDAR) subunits. NMDARs are ionotropic glutamate receptors that are crucial in excitatory neu...

Neurosciences (including psychophysiology)

  • 2024 - 2027
    • •
  • 6 894 tis. Kč
    • •
  • 6 894 tis. Kč
    • •
  • MZ
Project

Identification and analysis of genes and genetic defects causing rare neurodevelopmental disorders in children (NU22-07-00165)

Neurodevelopmental disorders include developmental delay, intellectual disability, behavioural disorders with autism spectrum disorders etc. They are a large group of rare diseases caused by defects in thousands genes. By analysing exomes and genomes...

Human genetics

  • 2022 - 2025
    • •
  • 13 502 tis. Kč
    • •
  • 13 502 tis. Kč
    • •
  • MZ
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