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9 (0,084s) •

Project

Hit-to-lead development of small molecules for enhanced medical radiation protection (NU23-08-00256)

radioprotective substance, amifostine, has successfully passed clinical trials, but it has of substances that showed a considerable radioprotective potential. The results of a pilot from this parent structure with radioprotecti...

Medicinal chemistry

  • 2023 - 2026
    • •
  • 12 589 tis. Kč
    • •
  • 12 430 tis. Kč
    • •
  • MZ
Project

Radioprotective Effects Induced by the Elevation of Extracellular Adeosine (GA306/93/0051)

ED - Fyziologie

  • 1993 - 1995
    • •
  • 323 tis. Kč
    • •
  • 646 tis. Kč
    • •
  • GA ČR
Project

Radioprotective effects of calcium antagonists usedalone or with cytokines (ROVLA50000060)

BO - Biofyzika

  • 1994 - 1995
    • •
  • 250 tis. Kč
    • •
  • 500 tis. Kč
    • •
  • MO
Project

Radioprotection and therapy of symptoms and complications in radiation damage (MO66020396301)

FP - Ostatní lékařské obory

  • 1996 - 1998
    • •
  • 1 625 tis. Kč
    • •
  • 1 625 tis. Kč
    • •
  • MO
Project

A Novel Non He-3 based Dual Neutron Gamma Sensor (7D17002)

Development, testing and validation the Novel NGSduo Product, i.e. a camera for imaging gamma and detection of neutron sources in nuclear decommissioning, nuclear safety, and environmental radioprotection. The goal is to sell and maintain th...

BA - Obecná matematika

  • 2017 - 2019
    • •
  • 15 952 tis. Kč
    • •
  • 7 976 tis. Kč
    • •
  • MŠMT
Project

Development of novel radioprotective agents based on small molecule inhibitors (GA17-13541S)

Radiotherapy is a very important modality for treating cancer. Its therapeutic potential is however limited by normal tissue damage, which leads to a wide range of symptoms (impeding quality of life of oncologic patients), prevents delivery of intend...

FD - Onkologie a hematologie

  • 2017 - 2019
    • •
  • 9 840 tis. Kč
    • •
  • 9 840 tis. Kč
    • •
  • GA ČR
Project

Development of production technology and application forms of glutathione with high bioavailibility for the suppression of oxidative stress (radiation, chemotherapy) (FR-TI3/496)

Development of technology of glutathione isolation in the frame of an industrial complex waste less fractionation of yeast biomass. The isolated glutathione will be incorporated into a nanoparticle carrier form ensuring its sufficient bioavailability...

GM - Potravinářství

  • 2011 - 2015
    • •
  • 29 479 tis. Kč
    • •
  • 20 022 tis. Kč
    • •
  • MPO
Project

Stepwise synthesis of oligosaccharides of 2-amino-2-deoxy sugars and preparation of their biologically important conjugates (GA203/96/0309)

of glycopeptides with immunostimulating, antiviral, antitumour, and radioprotective activity....

CC - Organická chemie

  • 1996 - 1998
    • •
  • 1 360 tis. Kč
    • •
  • 900 tis. Kč
    • •
  • GA ČR
Project

Preparation of multifunctional thermal responsive hydrogel for tumor-vascular normalization combined with radiation and immunotherapy (TF06000093)

The project is focused to preparation of immunoprotective nanopharmaceuticals suppressing the undesirable consequences of radio- and chemotherapy of tumors. The currently used chemical radioprotectant (Amifostin), which protects against gene...

Organic chemistry

  • 2019 - 2021
    • •
  • 17 771 tis. Kč
    • •
  • 12 440 tis. Kč
    • •
  • TA ČR
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