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3 230 (0,224s) •

Project

Stimuli-responsive giant vesicles for bio-applications (GN24-11194O)

The microfluidics (MC) technologies enable the formation of highly monodisperse particles with precise size control, improved encapsulation efficiency, and controlled compartmentalization. The main purpose of the project is to use MC for the producti...

Polymer science

  • 2024 - 2027
    • •
  • 6 115 tis. Kč
    • •
  • 5 638 tis. Kč
    • •
  • GA ČR
Project

Bottom-up unraveling of biophysical determinants of ORP5/8 mediated lipid transport using in vitro reconstitution and model membranes (GA19-18917S)

Membrane homeostasis requires organized transport of lipids from the endoplasmic reticulum (ER) to target membrane. Oxysterol binding protein related proteins (ORPs) represent a family of lipid transfer proteins, two members of which, ORP5/8, attract...

Biochemistry and molecular biology

  • 2019 - 2021
    • •
  • 3 705 tis. Kč
    • •
  • 3 705 tis. Kč
    • •
  • GA ČR
Project

In vitro reconstitution of viral “Replication factories“ (GJ15-21030Y)

of replication factories in vitro using the biomimetic giant unilamellar vesicle (GUV) system....

CE - Biochemie

  • 2015 - 2017
    • •
  • 5 551 tis. Kč
    • •
  • 5 551 tis. Kč
    • •
  • GA ČR
Project

Advanced stimuli-responsive giant vesicles – towards the mimicking of essential cell functions (LUAUS24137)

. Specifically, giant unilamellar vesicles (GUVs) have gained popularity in bottom-up the different types of artificial cells, giant vesicles have emerged as promising......

Analytical chemistry

  • 2024 - 2027
    • •
  • 6 755 tis. Kč
    • •
  • 6 755 tis. Kč
    • •
  • MŠMT
Project

The role of hydrophobic plasma membrane interior in DOR regulation of trimeric G protein activity (GAP207/12/0919)

unilamellar vesicles. Using cutting edge microscopy techniques (raster image correlation...

CE - Biochemie

  • 2012 - 2016
    • •
  • 9 965 tis. Kč
    • •
  • 9 965 tis. Kč
    • •
  • GA ČR
Project

Proteomic analysis of extracellular vesicles in Huntington's disease (GA19-01747S)

vesicles (EVs), mainly exosomes, are membraneous vesicles released by cells to body...

Neurosciences (including psychophysiology)

  • 2019 - 2022
    • •
  • 9 821 tis. Kč
    • •
  • 9 518 tis. Kč
    • •
  • GA ČR
Project

Characterization of immunomodulatory properties of extracellular vesicles derived from probiotic bacteria and their migration in the host (8J23AT019)

To verify the ability of vesicles obtained by probiotic E. coli O83 to reduce of these vesicles. 1. Aim to create E. coli O83 expressing fluorescent proteins that will subsequently be present in vesicles. Creation of E. col...

Microbiology

  • 2023 - 2024
    • •
  • 198 tis. Kč
    • •
  • 198 tis. Kč
    • •
  • MŠMT
Project

Extracellular vesicles produced by Bifidobacterium as novel approach for treatment of allergy diseases (GF23-04050L)

Bifidobacterium extracellular vesicles as immunomodulators in birch pollen allergy treatment/prevention. So far, the antiallergic properties of vesicles produced by Bifidobacterium characterize the extracellular vesicles o...

Microbiology

  • 2023 - 2025
    • •
  • 5 253 tis. Kč
    • •
  • 5 253 tis. Kč
    • •
  • GA ČR
Project

Study of the secretion of outer membrane vesicles in Francisella tularensis and their role in the interaction with the host (GA17-04010S)

biological warfare agent. Outer membrane vesicles secreted by gram-negative bacteria play interaction. Isolated vesicles of number of bacteria have also been studied for their immunomodulatory potential. F. tularensis secretes ...

EE - Mikrobiologie, virologie

  • 2017 - 2021
    • •
  • 5 945 tis. Kč
    • •
  • 5 945 tis. Kč
    • •
  • GA ČR
Project

Hyaluronan-catanionic vesicles complexes – interaction, structure, physical property, and stability (GC19-14024J)

Vesicles are self-closed hollow spheres with bilayer structures. The particular hydrophilic and hydrophobic active substances to be encapsulated. Catanionic vesicles. This project is focused on study of interaction between catanioni...

Physical chemistry

  • 2019 - 2023
    • •
  • 5 575 tis. Kč
    • •
  • 5 473 tis. Kč
    • •
  • GA ČR
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