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1 835 (0,093s) •

Project

Development of new methods for determination of vitamin D metabolites in biological material. (1A8634)

Developing and validation of method for determination of circulating endogenous vitamin D hydroxylated metabolites using immunochemical and chromatographic techniques with UV or fluorimetric detection of native or derivatized analyt...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2005 - 2007
    • •
  • 2 562 tis. Kč
    • •
  • 2 535 tis. Kč
    • •
  • MZ
Project

Strategies for increased vitamin D bioavailibity (EI22_002/0000865)

for the production of UVB-irradiated yeast with vitamin D content and the use of cell parts of such modified yeast to prepare a vitamin D delivery system with higher bioavailability using of an intelligent carrier...

Pharmacology and pharmacy

  • 2023 - 2026
    • •
  • 15 975 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MPO
Project

Utilization of Ultra High Performance Liquid Chromatography with mass spectrometry detection for determination of vitamin D and it’s metabolites for clinical practice (NT14265)

The project focuses on the development and validation of UHPLC methods for determination of vitamin D and its metabolites (25-OH D2, 25-OH D3) in human serum using studies of vitamin D metabolism, but also on the s...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2013 - 2015
    • •
  • 2 954 tis. Kč
    • •
  • 2 954 tis. Kč
    • •
  • MZ
Project

Bone mineral density, bone turnover and body composition in multiple sclerosis patients long-term treated with glucocorticoids relationships with vitamin D receptor allelic polymorphisms (NS10564)

-dose GS whether there is a relationship between vitamin D receptor gene polymorphisms and bone response to vitamin D3 plus calcium supplementation; 3) to identify......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2009 - 2011
    • •
  • 2 947 tis. Kč
    • •
  • 2 947 tis. Kč
    • •
  • MZ
Project

The role of vitamin D receptor in the pathogenesis of renal bone disease and postmenopausal osteoporosis (GA306/95/1151)

9G - 9

  • 1995 - 1995
    • •
  • 0 tis. Kč
    • •
  • 378 tis. Kč
    • •
  • GA ČR
Project

Modulation of mitochondrial functions in cancer cells by the mitochondrially targeted vitamin E analogues (GAP305/12/1708)

Our recent findings suggest that vitamin E analogues are novel anticancer drugs with considerable potential. They are able to induce apoptosis in cancer cells via targeting preliminary data suggest that mitochondrially targeted vitamin

EB - Genetika a molekulární biologie

  • 2012 - 2014
    • •
  • 4 944 tis. Kč
    • •
  • 4 944 tis. Kč
    • •
  • GA ČR
Project

Intracellular complement alterations in patients with allergic eosinophilic asthma. (NU20-05-00146)

system. Activation of CD4+ T cells can be pharmacologically influenced by vitamin D stimulation by anti-CD3 and anti-CD46 MAb in presence or absence of vitamin D. The effect of vitamin D will be ...

Immunology

  • 2020 - 2025
    • •
  • 12 372 tis. Kč
    • •
  • 12 290 tis. Kč
    • •
  • MZ
Project

Importance of local blood flow in bone tissue remodelation in rats-relations between bone blood circulation and bone metabolism.Hormonal regulations and other influences in model situations (NK5886)

Experimental study of relations of bone blood flow and bone tissue remodelation in laboratory conditions,caused by hormonal influence and by influence of other agents as STH,PTH,1,25 (OH)2 vitamin D,calcitonin and bisphosphonates. E...

FP - Ostatní lékařské obory

  • 2000 - 2002
    • •
  • 2 302 tis. Kč
    • •
  • 2 302 tis. Kč
    • •
  • MZ
Project

Plasma markers of coagulation activation in patients with endocardial electrode~ (NT14591)

According to literature, about 5 to 30% of patients with implanted pacemakers have asymptomatic or symptomatic venous thrombosis, but we use more often anti-platelet agents rather than anticoagulants. The project focuses on examination of hemocoagula...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2013 - 2015
    • •
  • 4 916 tis. Kč
    • •
  • 4 916 tis. Kč
    • •
  • MZ
Project

Therapy of rheumatoid arthritis with high doses of Vitamin E. (IZ2147)

9F - 9

  • 1994 - 1995
    • •
  • 165 tis. Kč
    • •
  • 330 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 1 835