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1 080 (0,118s) •

Project

MOLECULAR CYTOGENETIC ANALYSIS OF BRAIN TUMOUR CELLS AND ITS CONTRIBUTION TO DIAGNOSIS AND TREATMENT. (1A8237)

Molecular cytogenetic study of large cohort of patients with brain tumours. Identification of the most frequent chromosomal changes and evaluation of significance of single and cumulative cytogenetic aberrations for course and progn...

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 2 206 tis. Kč
    • •
  • 1 903 tis. Kč
    • •
  • MZ
Project

Classification of brain tumors using advanced techniques of multimodal diffusion MRI data (NU21-08-00359)

Brain tumours comprise a relatively rare disease, but one that is a significant cause of morbidity and mortality. Diagnosis of brain tumours, which is based mainly for non-invasive classification of brain ...

Radiology, nuclear medicine and medical imaging

  • 2021 - 2025
    • •
  • 7 373 tis. Kč
    • •
  • 7 332 tis. Kč
    • •
  • MZ
Project

Prognostic significance of apoptopic rate in relation to altered content of DNA in glial tumours of brain (NC4639)

Multifactorial analysis of relationship between apoptotic index (AI),ploidy and expression of gene products involved on regulation of apoptosis and proliferation in brain tumours. Determination of predictive validity of these factor...

EB - Genetika a molekulární biologie

  • 1998 - 2000
    • •
  • 1 444 tis. Kč
    • •
  • 1 444 tis. Kč
    • •
  • MZ
Project

Unique molecular biology of paediatric brain tumours associated with cancer predisposition syndromes (NU21-07-00419)

the incidence of cancer predisposition syndromes in children with brain tumours is unknown examine brain tumour tissue from patient with CPS using whole-exome sequencing of genetically and epigenetically defined <...

Human genetics

  • 2021 - 2024
    • •
  • 13 486 tis. Kč
    • •
  • 13 486 tis. Kč
    • •
  • MZ
Project

Preoperative delineation of the brain-meningioma barrier and its significance for choosing the therapetical modality. (NR7770)

Assessment of the state of the brain-meningioma barrier with methods of visualization (MRI of the brain, brain angiography) for the choice of optimal therapeutical modality in intracranial meningioma. A study of factors lik...

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 1 258 tis. Kč
    • •
  • 1 248 tis. Kč
    • •
  • MZ
Project

Role of cytotoxic gamma-delta T cells implicated in therapeutic resistence and tumour recurrence in Glioblastoma Multiforme (NV19-05-00410)

Glioblastoma multiforme (GBM) is the common malignant brain tumour in adults to the protected brain barrier and the immunosuppressive tumour microenvironment. New research highly reactive to GBM tumour. Th...

Immunology

  • 2019 - 2023
    • •
  • 9 480 tis. Kč
    • •
  • 9 439 tis. Kč
    • •
  • MZ
Project

Role of horizontal transfer of mitochondria in brain tumour formation (GA20-05942S)

to form brain tumours and that this is linked to de novo pyrimidine synthesis ratherOur recent research resulted in the discovery of horizontal transfer of mitochondria in vivo to breast cancer and melanoma cells with damaged mitoc...

Cell biology

  • 2020 - 2022
    • •
  • 9 817 tis. Kč
    • •
  • 9 817 tis. Kč
    • •
  • GA ČR
Project

Intraoperative identification of brain tumour tissue using Raman spectroscopy. (NV19-04-00281)

and allow for discerning between normal and tumour brain tissue in a minimal volume margins of tumour tissue, Raman spectroscopy uses spectral analysis to identify and characterise the spectra of a set of patients with gli...

Clinical neurology

  • 2019 - 2022
    • •
  • 7 532 tis. Kč
    • •
  • 7 532 tis. Kč
    • •
  • MZ
Project

Comparsion of results of electric cortical stimulation and functional magnetic resonance (NR7823)

The aim of the project is safe and radical surgery of intrinsic tumours in the eloquent areas of the brain (speech areas, motor areas), methodicaly using awake phase of surgery. Functional areas will be localised preoperatively by m...

FJ - Chirurgie včetně transplantologie

  • 2004 - 2006
    • •
  • 1 446 tis. Kč
    • •
  • 1 298 tis. Kč
    • •
  • MZ
Project

Immunohistochemical detection of nestin as a diagnostic marker in pathomorphology (NK6727)

Project is focused on the study of nestin expression during development of normal tissues and in tissues affected by certain types of disorders. Aim of the study is to judge a diagnostic and prognostic significance of imunohistochemical detection of ...

EA - Morfologické obory a cytologie

  • 2001 - 2003
    • •
  • 2 313 tis. Kč
    • •
  • 1 944 tis. Kč
    • •
  • MZ
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