All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Filters

27 (0,07s) •

Project

Synthetic lethal interactions of the mitochondrial integrated stress response in MYC-driven tumors (GA25-16629S)

therapy resistance in aggressive cancers that overexpress MYC transcription factors. Yet, molecular determinants that underlie the vulnerability of MYC-driven tumors and degradation of MYC proteins, this project will disse...

Cell biology

  • 2025 - 2027
    • •
  • 9 694 tis. Kč
    • •
  • 9 694 tis. Kč
    • •
  • GA ČR
Project

Templated synthesis and product characterization focused at development of potent and selective ligands of c-myc G-quadruplex (GA17-04393S)

Rational design of novel ligands of c-myc G-quadruplex is inherently difficult this shortcoming and identify novel binders of c-myc G-quadruplex we propose to explore in situ. Specifically, c-myc G-quadruplex will be explor...

CC - Organická chemie

  • 2017 - 2018
    • •
  • 4 135 tis. Kč
    • •
  • 2 994 tis. Kč
    • •
  • GA ČR
Project

Amplification of mycooncogenes and deletion of some suppressor genes in lung tumors. (IZ2291)

FD - Onkologie a hematologie

  • 1994 - 1997
    • •
  • 1 555 tis. Kč
    • •
  • 2 040 tis. Kč
    • •
  • MZ
Project

Autologous transplantation of purged neuroblastoma bone marrow grafts in children with high risk neuroblastoma. (IZ2067)

FD - Onkologie a hematologie

  • 1994 - 1998
    • •
  • 3 415 tis. Kč
    • •
  • 4 320 tis. Kč
    • •
  • MZ
Project

A continuum model for tumour suppressor mechanism orchestrated by the Hippo signalling pathway. (GP14-21095P)

remain unknown. Our preliminary data suggest role for C-MYC oncoprotein. In this project we will analyze molecular mechanism responsible for regulation of C-MYC......

EB - Genetika a molekulární biologie

  • 2014 - 2016
    • •
  • 2 448 tis. Kč
    • •
  • 2 448 tis. Kč
    • •
  • GA ČR
Project

Molecular-biologic prognostic signs in bone and brain tumours of childhood (GA301/00/1394)

of specific chromosomal aberrations (amplification c-myc and N-myc, deletion of 17p...

FD - Onkologie a hematologie

  • 2000 - 2002
    • •
  • 3 036 tis. Kč
    • •
  • 3 036 tis. Kč
    • •
  • GA ČR
Project

Changes in the structure of interphase nucleai of human leukemic cell lines after treatment with differentiating agents and gama irradiation (GA202/98/P253)

, the reverse transcription polymerase chain reaction (RT-PCR) for c-myc and abl-bcr gene expression will be applied. C-myc protooncogene plays an essential role in the regulation......

EB - Genetika a molekulární biologie

  • 1998 - 2001
    • •
  • 768 tis. Kč
    • •
  • 708 tis. Kč
    • •
  • GA ČR
Project

Nuclear topology of some protooncogenes in human neutrophilic granulocytes and leukemic cells (IAB5004102)

The project will study the topology of C-MYC, ABL and BCR protoocogenes in the nuclei of human granulocytes in comparison with the topology of mentioned genes in leukemic cells that will be differentiated along the myeloid pathway taht chrom...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 1 924 tis. Kč
    • •
  • 694 tis. Kč
    • •
  • AV ČR
Project

Molecular diagnosis of the lymphoproliferative disorders with methods of analysis of DNA, RNA and proteins application of results in clinical praxis (NR8443)

lymphocytes with distinctive translocation t(11;14)(q13;q32). C-myc and p16 genes...

EB - Genetika a molekulární biologie

  • 2005 - 2007
    • •
  • 2 222 tis. Kč
    • •
  • 2 207 tis. Kč
    • •
  • MZ
Project

Biomarkers for optimization of the treatment of soft - tissue sarcomas (NM14)

The project implements the methods of molecular biology to detect the biological properties of soft tissue sarcomas in clinical practice and aims optimize the therapeutic decision-making in individual cases. The biomarkers analyzed for their predicti...

FD - Onkologie a hematologie

  • 1998 - 2000
    • •
  • 1 292 tis. Kč
    • •
  • 1 028 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 27