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1 307 (0,153s) •

Project

Exploring the impact of somatic expansion rates on quantitative progression marker candidates (Voice) in early stages of Repeat Expansion Disorders (9F25002)

Aim 1: Identify and characterize molecularly a population of patients carrying repeat expansion mutations at early disease stages/prodromal (within 5 years to predicted onset) by determining the length of the uninterrupted triplet repeat str...

Clinical neurology

  • 2025 - 2028
    • •
  • 6 206 tis. Kč
    • •
  • 6 206 tis. Kč
    • •
  • MŠMT
Project

Diagnostics of Lewy body diseases in prodromal stage based on multimodal data analysis (NU20-04-00294)

to identify prodromal biomarkers of LBDs and describe underlying pathophysiological...

Neurosciences (including psychophysiology)

  • 2020 - 2024
    • •
  • 11 556 tis. Kč
    • •
  • 11 556 tis. Kč
    • •
  • MZ
Project

Prodrome of the Prague Flora. (KZ97P010MG116)

EF - Botanika

  • 1997 - 1997
    • •
  • 44 tis. Kč
    • •
  • 20 tis. Kč
    • •
  • MK
Project

REM sleep behavior disorder predicting the risk of neurodegeneration (GA16-07879S)

Idiopathic REM sleep behavior disorder (iRBD) characterized by dream enactment behavior associated with loss of REM sleep muscle atonia is recognized as prodromal stage of neurodegenerative synucleinopathy. By studying a cohort of approx. 10...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2020
    • •
  • 7 179 tis. Kč
    • •
  • 7 179 tis. Kč
    • •
  • GA ČR
Project

The experimental memory paradigms of encoding and storage in early stages of Alzheimer´s disease (GA22-33968S)

designed to detect the disease during the prodromal stage of mild cognitive impairment markers of typical AD, it seems to be crucial to explore more challenging paradigms......

Psychology (including human - machine relations)

  • 2022 - 2024
    • •
  • 7 353 tis. Kč
    • •
  • 7 353 tis. Kč
    • •
  • GA ČR
Project

ITAREPS 2.0 study Prospective, randomized, open, controlled study with information and telecommunication technology-aided relapse prevention program in schizophrenia. (NT13292)

The ITAREPS 2.0 program employs telecommunication and information technologies in order to detect fluctuations in longitudinal mental health status of patient with schizophrenia and thus signalize the very early stages of prodromes preceding...

FL - Psychiatrie, sexuologie

  • 2012 - 2014
    • •
  • 4 665 tis. Kč
    • •
  • 4 665 tis. Kč
    • •
  • MZ
Project

Prevalence of high risk symptoms for psychosis and their relationship to neurocognitive performance and daily functioning in population of adolescents (GA18-03125S)

Schizophrenia is a severe mental illness that usually develops during adolescence. Fully developed disease is usually preceded few years earlier by the prodromal phase, which is characterized by typical symptoms like attenuated psychotic too...

Psychology, special (including therapy for learning, speech, hearing, visual and other physical and mental disabilities);

  • 2018 - 2023
    • •
  • 4 981 tis. Kč
    • •
  • 4 447 tis. Kč
    • •
  • GA ČR
Project

Synucleinopathy - gut microbiota, pathophysiology, and biomarkers of progression (NW25-04-00079)

is preceded by a prodromal period with isolated REM sleep behavior disorder (iRBD). One will be correlated with robust clinical markers of synucleinopathy from routine examinations the progression of these individual markers

Neurosciences (including psychophysiology)

  • 2025 - 2028
    • •
  • 18 857 tis. Kč
    • •
  • 18 857 tis. Kč
    • •
  • MZ
Project

Investigating evolution of speech disorder in Parkinson's disease via objective acoustic analysis (NW24-04-00211)

for the first time evolution of speech disorder in PD from prodromal stages of disease prodromal to more advanced stages of disease (EVOLSPEECH-PD) would have a very high......

Clinical neurology

  • 2024 - 2027
    • •
  • 15 260 tis. Kč
    • •
  • 15 260 tis. Kč
    • •
  • MZ
Project

Biomarkers of neurodegenerative diseases based on dynamic functional connectivity (NU21J-04-00077)

, sensitive to prodromal states of neurodegenerative disease, may improve timing of FC have a great potential to become useful biomarkers of prodromal stages activity. In this project we want to focus on search for biomarkers of

Clinical neurology

  • 2021 - 2025
    • •
  • 4 962 tis. Kč
    • •
  • 4 962 tis. Kč
    • •
  • MZ
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