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Involvement of nuclear HMGB proteins in sensitizing of human cells to anticancer drugs inhibiting DNA topoisomerases (GAP301/10/0590)
relationship between HMGB-type proteins, tumor suppressor pRb and DNA topoisomerases (Štros of topoisomerases I and II (topo) by HMGB-type proteins and/or pRb will be investigated innormal expression of HMGB proteins on nu...
FD - Onkologie a hematologie
- 2010 - 2012 •
- 4 859 tis. Kč •
- 4 859 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2010 - 31. 12. 2012
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
HMGB proteins involvement in biology of telomeres and human embryonic stem cells (GAP305/12/2475)
the impact of deregulated expression of HMGB1 or other HMGBs (silencing by shRNA into differentiation pathway, we will address the possible involvement of HMGBs in maintenance of HMGBs in modulation of telomerase activity,...
EB - Genetika a molekulární biologie
- 2012 - 2015 •
- 9 740 tis. Kč •
- 9 740 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2012 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Alarmins in the development and diagnostics of septic complications of tissue injury (NV15-30186A)
Increased susceptibility to infections is a frequent complication of tissue injury elicited by trauma, surgical procedure or invasive infection. We suppose that the major role in the development of infectious complications is played by alarmins (i.e....
FN - Epidemiologie, infekční nemoci a klinická imunologie
- 2015 - 2018 •
- 6 719 tis. Kč •
- 6 719 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2015 - 31. 12. 2018
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
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