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83 (0,078s) •

Project

Combined therapy of minimal residual disease using IL-2 and GM-CSF as recombinant cytokines or genetically modified vaccines (NC5526)

The grant project is aimed at a combined therapy of tumours using IL-2 and GM-CSF as recombinant cytokines or genetically modified tumour vaccines.......

FD - Onkologie a hematologie

  • 1999 - 2001
    • •
  • 2 856 tis. Kč
    • •
  • 2 566 tis. Kč
    • •
  • MZ
Project

The role of signalling through adenosine receptors and its interaction with G-CSF in regulation of haematopoiesis (GP305/03/D050)

for haematopoietic progenitor cell for granulocytes and macrophages (GM-CFC). The production of selected haematopoietic growth factors, namely GM-CSF, G-CSF and IL-6, in serum in the frame of the garant's project,...

FR - Farmakologie a lékárnická chemie

  • 2003 - 2006
    • •
  • 677 tis. Kč
    • •
  • 677 tis. Kč
    • •
  • GA ČR
Project

Vaccination against two types (MHC I+ and MHC I-) of tumours induced by E6/E7 HPV16 viral oncogenes. (NC7148)

projectby insertion of IL-2 and GM-CSF genes into HPV16+ tumour cells The research will also be focused on the therapeutic effects of IL-2, IL-12 and GM-CSF cytokines......

FD - Onkologie a hematologie

  • 2002 - 2004
    • •
  • 5 395 tis. Kč
    • •
  • 3 375 tis. Kč
    • •
  • MZ
Project

Determination of functional activities and phenotype of tumor infiltrating lymphocytes in patients with ovarian cancer (NH5196)

This is project destined to investigate the potential role of adoptive ommunotherapy in the treatment of ovarian cancer.Preclinical data on henotype and cytotoxic activity of TIL,and concentrations of markers of immune activation in malignit. In the ...

EC - Imunologie

  • 1999 - 2001
    • •
  • 944 tis. Kč
    • •
  • 944 tis. Kč
    • •
  • MZ
Project

Imunization against Tumors Characterized by Different Escape Mechanisms (NC7552)

IL-12, GM-CSF, Flt3L, IL-2 or soluble TGF-beta type II receptor. Immunization...

FD - Onkologie a hematologie

  • 2003 - 2005
    • •
  • 12 151 tis. Kč
    • •
  • 11 594 tis. Kč
    • •
  • MZ
Project

Gene therapy of cancer utilisation of the synergistic effects of antitumor cytokines (GA301/00/P021)

, IFN alpha, IFN gamma and GM-CSF. The optimal combination of cytokines...

EB - Genetika a molekulární biologie

  • 2000 - 2002
    • •
  • 216 tis. Kč
    • •
  • 216 tis. Kč
    • •
  • GA ČR
Project

ASKD - GM - Mobile shop device for maintenance and repairs of special tracked chassis frames (ORVTUPV200603)

The main goal of project solving is to develop and verify mobile shop device ASKD-GM intendent for carryying out of maintenance and routine repairs of special tracked chassis GM 568, GM 578 and power generating sets GTD-5 a...

KA - Vojenství

  • 2006 - 2007
    • •
  • 19 987 tis. Kč
    • •
  • 19 987 tis. Kč
    • •
  • MO
Project

Enhancement of G-CSF action by adenosine signalling testing of its potential clinical use in murine models (GA306/99/0027)

effects of granulocyte colony-stimulating factor (G-CSF) and drugs elevating with respect to the clinical use of G-CSF. Interactions of G-CSF with dipyridamole and AMP will be studied in the following two experimental situ...

ED - Fyziologie

  • 1999 - 2001
    • •
  • 2 397 tis. Kč
    • •
  • 1 821 tis. Kč
    • •
  • GA ČR
Project

Use of dendritic cells infected by attenuated recombinant vaccinia viruses for eliciting of specific immune response (GA310/99/0543)

of cytokines IL-12 and GM-CSF in VV on antigen presenting ability of DC. 4) To determinethe...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1999 - 2001
    • •
  • 2 745 tis. Kč
    • •
  • 2 625 tis. Kč
    • •
  • GA ČR
Project

Mechanisms underlying cyclophosphamide-induced accumulation of myeloid derived suppressor cells (GPP301/11/P220)

cyclophosphamide chemotherapy (role of proinflammatory cytokines such as VEGF, IL-1, and GM-CSF...

FD - Onkologie a hematologie

  • 2011 - 2013
    • •
  • 1 800 tis. Kč
    • •
  • 1 800 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 83