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6 (0,125s)

Project

Engineering next-generation thrombolytics for the treatment of stroke (GM25-18233M)

Acute ischemic stroke is the second leading cause of death. It is caused by fibrin clots blocking blood flow to the brain. Thrombolytics are practical methods to develop the next-generation thrombolytics to overcome these limitation...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2025 - 2029
  • 24 890 tis. Kč
  • 24 890 tis. Kč
  • GA ČR
Project

Advancing New Thrombolytic Testing An Innovative Model Harnessing Precise Clot Structure and its Interaction with Vessel Wall under Simulated Pathophysiological Conditions (NW24-08-00064)

thrombolytic treatment is currently clinically approved, it has relatively low success overlooked in the design of thrombolytics. To facilitate research of thrombolytics screening of different types of thrombolytics

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2024 - 2027
  • 13 617 tis. Kč
  • 13 617 tis. Kč
  • MZ
Project

Biocompatible nanoparticles tailored as targeted drug delivery systems and theranostics for treatment of stroke (NU21-08-00510)

the thrombolytic effect of recombinant plasminogen and alteplase. These thrombolytics thrombolytics for the diagnosis and treatment of stroke in a preclinical animal model (rat......

Nano-materials (production and properties)

  • 2021 - 2025
  • 15 038 tis. Kč
  • 15 038 tis. Kč
  • MZ
Project

Improving the efficacy and safety of recanalization of cerebral infarction with dual thrombolytic therapy (NU23-08-00499)

infarction is the insufficient effectiveness (recanalization ability) of thrombolytic therapy. Thrombolytic therapy is and will remain the first line of recanalization a more effective thrombolytic strategy through a combi...

Neurosciences (including psychophysiology)

  • 2023 - 2026
  • 10 110 tis. Kč
  • 10 110 tis. Kč
  • MZ
Project

Assessment of the Prognosis and the Incidence of Complication in Sclerotic and Diabetic Angiopathy of Vessels of the Lower Limbs. (NA6408)

The authors will perform a complete clinical examination, a morphological and a functional assessment of the vascular wall, an examination of thrombolytic activity parameters, of fibrin degradation products, and of adhesive molecules. The gr...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2000 - 2002
  • 2 523 tis. Kč
  • 2 522 tis. Kč
  • MZ
Project

Engineering of new biomaterials and biopharmaceuticals for the diagnosis and treatment of the cerebrovascular and neurodegenerative diseases (EF16_026/0008451)

The main objectives of this project address the complex issues outlined in the previous section thanks to the unique expertise and long-term experience of academic, clinical and industrial partners involved. Applicant and project partners will bene...

Biochemistry and molecular biology

  • 2018 - 2023
  • 112 031 tis. Kč
  • 31 337 tis. Kč
  • MŠMT
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