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13 616 (0,129s)

Project

The role of interaction of cytochrome P-450 metabolites and the renin-angiotensin system in the control of renal function (NR8271)

The role of interaction of cytochrome P-450 metabolites and the renin-angiotensin system in the control of renal function and development of angiotensin II-dependent hypertension will be studied.......

FP - Ostatní lékařské obory

  • 2005 - 2007
  • 4 904 tis. Kč
  • 4 773 tis. Kč
  • MZ
Project

A new insight on the role of the renin-angiotensin system in blood pressure regulation and development of hypertension-a study in transgenic rats with inducible hypertension (NR7956)

The role of the renin-angiotensin system in the control of blood pressure and development of hypertension will be studied in transgenic rats with inducible hypertension.......

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2004 - 2006
  • 3 213 tis. Kč
  • 3 188 tis. Kč
  • MZ
Project

The interaction between renin-angiotensin and endothelin systems in the pathogenesis of renal failure and cardiac hypertrophy in hypertensive rats (NS10500)

Potential additive effect of the treatment wirh endothelin receptor blocker (atrasentan) to low salt diet and renin-angiotensin system blockade in a rat model transenic for mouse renin gene and/or 5/6 nephrectomy w...

FE - Ostatní obory vnitřního lékařství

  • 2009 - 2011
  • 3 942 tis. Kč
  • 3 942 tis. Kč
  • MZ
Project

The role of angiotensin-(1-7), a new component of the renin-angiotensin system, in the pathophysiology of two-kidney one-clip Goldblatt hypertension (IAA511700701)

The renin-angiotensin system (RAS) plays a key role in the regulation of arterial blood pressure and in the development of hypertension. Angiotensin II has been of the RAS. Increasing evidence suggest that angi...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2007 - 2009
  • 2 427 tis. Kč
  • 2 427 tis. Kč
  • AV ČR
Project

The role of a new vasodilatory axis of the renin-angiotensin system in the pathophysiology of hypertension potencially new therapeutic approach in hypertension treatment. (NT14085)

The renin-angiotensin system (RAS) plays the important role in the regulation of blood pressure, renal and cardiovascular functions. Within the RAS two axes exist: "vasoconstrictor axis" represented by production and degrad...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2013 - 2015
  • 4 834 tis. Kč
  • 4 834 tis. Kč
  • MZ
Project

The Renin-Angiotensin System and Hypertension Effects of Blockade of AT1 Receptors by Specific Antibody (GA306/94/1480)

ED - Fyziologie

  • 1994 - 1996
  • 537 tis. Kč
  • 804 tis. Kč
  • GA ČR
Project

The role of impairment of pressure-natriuresis mechanism in the pathophysiology of angiotensin II-dependent malignant form of hypertension (NS10499)

The role of impaired pressure-natriuresis mechanism in the pathophysiology of angiotensin II-induced malignant form of hypertension will be studied.......

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2009 - 2011
  • 3 762 tis. Kč
  • 3 762 tis. Kč
  • MZ
Project

Role of the renin-angiotensin system in the control of renal function and blood pressure studies in the "knock-out" mouse with AT1A receptor absence. (NA5291)

In mice with genetically evoked absence of AT-1 receptor for angiotensin II, which cannot respond to own endogenous angiotensin, the role of this autacoid for development and maintenance of blood pressure and renal function will be ...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 1999 - 2001
  • 3 349 tis. Kč
  • 3 349 tis. Kč
  • MZ
Project

The role of the interaction of the AT1 and AT2 angiotensin II receptors in the ontogenesis of hypertension a study in "Ren-2" transgenic rats (NR8550)

The role of the interaction of the AT1 and AT2 angiotensin II receptors in the ontogenesis of hypertension will be studied in the model of "Ren-2" transgenic rats.......

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2005 - 2007
  • 4 838 tis. Kč
  • 4 728 tis. Kč
  • MZ
Project

The role of interaction of the cytochrome P450-derived eicosanoids and the renin-angiotensin system in the pathophysiology of congestive heart failure combined with chronic kidney disease. (NT14012)

Recent studies have proposed that in the pathophysiology of progression of congestive heart failure combined with chronic kidney disease rather the interaction of renin-angiotensin-aldosterone system (RAAS) with other vasoa...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2013 - 2015
  • 5 211 tis. Kč
  • 5 211 tis. Kč
  • MZ
  • 1 - 10 out of 13 616