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10 (0,054s) •

Project

Study of hypervirulent complexes of Neisseria meningitidis by methods of molecular biology and possibility of their prevention in the Czech Republic by vaccination (1A8688)

of invasive meningococcal disease in the Czech Republic. Multilocus sequence typing (MLST) willbe the method preferably used for clonal analysis in this project. The MLST data will be sent to the world-wide central MLST da...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2005 - 2007
    • •
  • 5 525 tis. Kč
    • •
  • 4 107 tis. Kč
    • •
  • MZ
Project

Analyzing the sources of human Campylobacter infections, antibiotic resistance of thermotolerant Campylobacter spp. and epidemiology of campylobacterioses (NT14392)

of MALDI-TOF MS will be compared with the PFGE and MLST. The prevalence as PFGE and MLST. Susceptibility to antibiotic will be determined by the microdilution......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2013 - 2015
    • •
  • 6 205 tis. Kč
    • •
  • 6 205 tis. Kč
    • •
  • MZ
Project

Molecular surveillance of invasive pneumococcal disease in the Czech Republic, assessment of vaccination strategy and recommendation for update (NV17-29256A)

; molecular characterization by MLST (Multi Locus Sequence Typing), MLVA (Multi Locus...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2017 - 2021
    • •
  • 6 516 tis. Kč
    • •
  • 6 195 tis. Kč
    • •
  • MZ
Project

Molecular identification of bacterial strains which cause severe epidemics in Czech patients with cystic fibrosis and prevention of their spread within this population (NS10543)

tested by MLST to get unambiguous strain identification and the modified MLST method...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2009 - 2011
    • •
  • 4 687 tis. Kč
    • •
  • 4 687 tis. Kč
    • •
  • MZ
Project

Contributing potential of MALDI-TOF spectrometry and HRMA in identification and typing of bacterial pathogens – evaluation on the model of COPD, bronchiectasis and cystic fibrosis (NT13560)

The project consists in a conclusive prospective study of performance of MALDI-TOF spectrometry and High Resolution Melting Analysis of PCR-products (PCR-HRMA) in species identification, and MALDI-TOF and McRAPD in strain typing, compared to referenc...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2012 - 2015
    • •
  • 3 539 tis. Kč
    • •
  • 3 539 tis. Kč
    • •
  • MZ
Project

Classification of biological agents ? support of an international project ?Establishment and management of a common database of B-agents ? A European Laboratory Biodefence Network (OVUOFVZ200901)

The goal of the project is to gather typing data for B-agents listed in project of the european biological database by the mean of mass spectrometry (MALDI-TOF, tandem mass spectrometry) and molecular biology (real-time PCR, MLST).......

EE - Mikrobiologie, virologie

  • 2009 - 2011
    • •
  • 15 788 tis. Kč
    • •
  • 13 221 tis. Kč
    • •
  • MO
Project

Molecular epidemiology of invasive meningococcal disease in the Czech Republic. (NV15-34887A)

The objective of this project is to set up the molecular surveillance of invasive meningococcal disease in the Czech Republic to be able to distinguish between vaccine failure and non-coverage by vaccine and to update the vaccination strategy recomm...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2015 - 2018
    • •
  • 6 650 tis. Kč
    • •
  • 6 329 tis. Kč
    • •
  • MZ
Project

Molecular determinants of Streptococcus agalactiae strains in relation to the invasiveness of the infection (NR9432)

The introduction of the method of multi-locus sequence typing for Streptococcus agalactiae shall render possible the comparison of Czech hyper-virulent clones with those from abroad. Knowledge of the distribution of genes of the potential factors of ...

EE - Mikrobiologie, virologie

  • 2007 - 2009
    • •
  • 3 375 tis. Kč
    • •
  • 3 330 tis. Kč
    • •
  • MZ
Project

Study of the usability of meningococcal vaccines designed using reverse vaccinology methods in the Czech Republic (NT11424)

will also be characterized by molecular methods (MLST, and PorA, FetA and PenA...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2010 - 2013
    • •
  • 5 769 tis. Kč
    • •
  • 5 769 tis. Kč
    • •
  • MZ
Project

Proteomic profiling of Cronobacter strains focused on the incidence of virulent proteins (GA13-23509S)

Members of the genus Cronobacter, formerly known as Enterobacter sakazakii, are foodborne pathogens often implicated in serious neonatal infections. The severity of Cronobacter-related infections forced scientists into intense investigation of Cronob...

GM - Potravinářství

  • 2013 - 2016
    • •
  • 5 981 tis. Kč
    • •
  • 5 981 tis. Kč
    • •
  • GA ČR
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