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3 024 (0,152s) •

Project

Congenital heart disease - protein and phospholipids remodelation of atrial and ventricular part of heart and muscle, the role of scavengers (NA6496)

The study of protein, phospholipid and scavenger composition of atrial and ventricular musculature in children with normoxemic and hypoxemic congenital heart disease. Biochemical remodelation of heart musculature in congenital heart disease....

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2001 - 2003
    • •
  • 1 631 tis. Kč
    • •
  • 1 611 tis. Kč
    • •
  • MZ
Project

Membrane Currents and Contractility of Cardiac Cells (GA305/93/0169)

ED - Fyziologie

  • 1993 - 1995
    • •
  • 535 tis. Kč
    • •
  • 1 070 tis. Kč
    • •
  • GA ČR
Project

Transmembrane ionic currents of heart cells and their relation to contractility. Influence of antiarrhytmics. (IZ1411)

9F - 9

  • 1993 - 1995
    • •
  • 79 tis. Kč
    • •
  • 158 tis. Kč
    • •
  • MZ
Project

Tropomyosin isoform Tpm2.3 in regulation of actin dynamics and osteosarcoma metastasis (GF23-06303K)

Actin cytoskeleton is a complex and dynamic network of filaments maintaining cell shape, tension, contractility, adhesion, migration, and intracellular of actin-binding proteins. Access of actin-binding proteins to actin f...

Cell biology

  • 2023 - 2025
    • •
  • 5 556 tis. Kč
    • •
  • 5 556 tis. Kč
    • •
  • GA ČR
Project

Changes in global and regional parameters of myocardial contractility in patients after heart transplantation. (NS10627)

In patients after orthotopic heart transplantation, will will assess very subtle global and regional parameters of myocardial contractility using a new ultrasound technique - speckle tracking echocardiography. These parameters will be first:...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2009 - 2011
    • •
  • 1 386 tis. Kč
    • •
  • 1 386 tis. Kč
    • •
  • MZ
Project

Cardioprotective mechanisms of chronic intermittent and sustained hypoxia role of reoxygenation. (GA305/07/0875)

of oxidant stress and some related factors and pathways (protein kinase C, tumor necrosis factor alpha, uncoupling proteins, antioxidant enzymes) in the pathogenesis contractile dysfunction and the incidence and severity o...

ED - Fyziologie

  • 2007 - 2009
    • •
  • 3 089 tis. Kč
    • •
  • 3 089 tis. Kč
    • •
  • GA ČR
Project

Revealing the Mechanism of Neural Tube Formation (GA22-06405S)

that protein Prickle2 promotes ApCo by locally controlling actomyosin contractile machinery is manifested by the oriented localization of ‘core’ PCP protein components. Mutations......

Developmental biology

  • 2022 - 2024
    • •
  • 6 444 tis. Kč
    • •
  • 6 444 tis. Kč
    • •
  • GA ČR
Project

Altered regulation of vasoactive system balance in experimental hypertension (GA305/08/0139)

vasoconstriction in hypertensive rats will be studied by evaluating 1) in vitro contractile of Gi proteins and Ca2+ influx through voltage-dependent Ca2+ channels) and 2......

ED - Fyziologie

  • 2008 - 2010
    • •
  • 4 854 tis. Kč
    • •
  • 4 854 tis. Kč
    • •
  • GA ČR
Project

Role of K(ATP) channels in cardioprotective mechanisms induced by chronic hypoxia (GA305/04/0465)

potential involvement of some of the downstream protein kinase signaling pathways; the size of myocardial infarction, post-ischemic contractile dysfunction......

ED - Fyziologie

  • 2004 - 2006
    • •
  • 2 716 tis. Kč
    • •
  • 2 716 tis. Kč
    • •
  • GA ČR
Project

Intracoronary versus intramyocardial autologous bone marrow stem cell transplantation into a focus of nonviable myocardium. (NR8143)

regeneration (neogenesis of contractile and vascular structures). We propose to verify provoke a contractility, metabolism and perfusion improvement of diseased area......

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2004 - 2006
    • •
  • 689 tis. Kč
    • •
  • 624 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 3 024