All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Filters

5 395 (0,064s) •

Project

Complexes of IL-2 and anti-IL-2 mAb with selective stimulatory activity for CD25+ T cells in cancer immunotherapy changing the paradigm (GA22-20548S)

Complexes of IL-2 and anti-IL-2 mAbs possess extremely high biological activity in vivo. Moreover, such IL-2 complexes have selective stimulatory activity for different IL-2 responsive cells depending on the clone ...

Oncology

  • 2022 - 2024
    • •
  • 8 330 tis. Kč
    • •
  • 8 330 tis. Kč
    • •
  • GA ČR
Project

Strong sustained IL-2 signal selectively targeted to CD25+ cells dramatically increases sensitivity to LPS-mediated mortality finding the mechanism (GA13-12885S)

It has been shown previously that complexing IL-2 with certain anti-IL-2 mAb enourmously increases activity of IL-2 in vivo. These immunocomplexes selectively stimulate different subsets of immune cells depending on clone ...

EC - Imunologie

  • 2013 - 2018
    • •
  • 11 872 tis. Kč
    • •
  • 11 872 tis. Kč
    • •
  • GA ČR
Project

IL-2 complexed with muteins of JES6-1 mAb having different affinity to IL-2 finding variant with most selective stimulation of Treg cells in vivo (GA18-12973S)

Complexes of IL-2 and anti-IL-2 mAb JES6-1 potently expand CD25+ cells, i.e to understanding the mechanism how these complexes interact with high affinity trimeric IL-2 receptor. JES6-1 mAb sterically blocks the interaction...

Immunology

  • 2018 - 2022
    • •
  • 4 804 tis. Kč
    • •
  • 4 762 tis. Kč
    • •
  • GA ČR
Project

*Modernization of the VS 2 ejection seat. (FT-TA3/046)

*Modernization of the VS 2 ejection seat....

JU - Aeronautika, aerodynamika, letadla

  • 2006 - 2008
    • •
  • 35 869 tis. Kč
    • •
  • 18 212 tis. Kč
    • •
  • MPO
Project

Study of anion processes relevant for astrophysics (7AMB14AT023)

The primary objective of the project on the czech side is the measurement of the temperature dependence of the rate coefficients of O - + H 2 -> H 2 O + e - O - + H 2 of the isotopicexchange H 2 /D 2 . The...

CF - Fyzikální chemie a teoretická chemie

  • 2014 - 2015
    • •
  • 200 tis. Kč
    • •
  • 200 tis. Kč
    • •
  • MŠMT
Project

Aspects of immune response and efficacy of booster dose of SARS-CoV-2 mRNA vaccine in kidney transplant recipients (NU22-C-126)

1) Evaluate safety and imunogenicity of booster dose of SARS-CoV-2 mRNA vaccine in kidney transplant recipients. 2) Evaluate association between booster dose of SARS-CoV-2 mRNA vaccine and risk of SARS-CoV-2 infect...

Transplantation

  • 2022 - 2023
    • •
  • 6 194 tis. Kč
    • •
  • 6 194 tis. Kč
    • •
  • MZ
Project

Synthesis of nonracemic helical aromatics employing transition metal catalysis (GA203/07/1664)

: (a) diastereoselective [2+2+2] cyclotrimerisation of aromatic triynes containing two asymmetric) diastereoselective [2+2+2] cyclotrimerisation of chiral complexes of pyridine triynes with chiral...

CC - Organická chemie

  • 2007 - 2009
    • •
  • 3 059 tis. Kč
    • •
  • 3 059 tis. Kč
    • •
  • GA ČR
Project

Arrangement of the participation in the OECD MCCI - 2 project and using of its results (LA 295)

participation in OECD MCCI - 2 project, investigation of mechanisms of heat divertion at interaction melt - concrete...

JF - Jaderná energetika

  • 2006 - 2009
    • •
  • 4 210 tis. Kč
    • •
  • 1 790 tis. Kč
    • •
  • MŠMT
Project

Novel clinically relevant IL-2 immunotherapeutics for cancer treatment (GA20-13029S)

Mouse IL-2/S4B6 mAb complexes with potent stimulatory activity for memory CD8 IL-2. Potential clinical use of these complexes is limited due to the mouse origin of IL-2 and dissociation of the complexes at low concentration...

Immunology

  • 2020 - 2022
    • •
  • 12 596 tis. Kč
    • •
  • 12 596 tis. Kč
    • •
  • GA ČR
Project

FGF-2 and FGFR-3 in chronic myeloid leukemia. A study on model leukemia cell lines and on CD34+ progenitor cells from patients (GA301/03/1122)

factor 2 (FGF-2) in plasma and up-regulation of myeloma-associated proto-oncogene synthesize multiple isoforms of FGF-2. To investigate functional consequenceofdysregulated expression of FGF-2 and FGFR-3 in CD34+ ...

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 3 540 tis. Kč
    • •
  • 2 340 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 5 395